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18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide

(R)-2-(4-FLUOROPHENYL)PIPERIDINE synthesis

5synthesis methods
6-(4-Fluoro-phenyl)-2,3,4,5-tetrahydro-pyridine

509953-48-4
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(R)-2-(4-FLUOROPHENYL)PIPERIDINE

1187468-22-9
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Yield:91 % ee

Reaction Conditions:

with (R)-imine reductase from Streptomyces sp GF3587 for 24 h;enantioselective reaction;

References:

Hussain, Shahed;Leipold, Friedemann;Man, Henry;Wells, Elizabeth;France, Scott P.;Mulholland, Keith R.;Grogan, Gideon;Turner, Nicholas J. [ChemCatChem,2015,vol. 7,# 4,p. 579 - 583]

149437-76-3 Synthesis
4-(4-Fluorobenzoyl)butyric acid

149437-76-3
367 suppliers
$8.00/10g

(R)-2-(4-FLUOROPHENYL)PIPERIDINE

1187468-22-9
17 suppliers
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References
6-(4-Fluoro-phenyl)-2,3,4,5-tetrahydro-pyridine

509953-48-4
3 suppliers
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(R)-2-(4-FLUOROPHENYL)PIPERIDINE

1187468-22-9
17 suppliers
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(S)-2-(4-FLUOROPHENYL)PIPERIDINE

1187468-21-8
22 suppliers
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References
14660-52-7 Synthesis
Ethyl 5-bromovalerate

14660-52-7
233 suppliers
$6.00/5g

(R)-2-(4-FLUOROPHENYL)PIPERIDINE

1187468-22-9
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References
5-bromo-Pentanal

1191-30-6
12 suppliers
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(R)-2-(4-FLUOROPHENYL)PIPERIDINE

1187468-22-9
17 suppliers
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References