ChemicalBook CAS DataBase List (R)(-)-2-BENZYLAMINO-1-BUTANOL

(R)(-)-2-BENZYLAMINO-1-BUTANOL synthesis

10synthesis methods

Product Name:(R)(-)-2-BENZYLAMINO-1-BUTANOL
CAS Number:6257-49-4
Molecular formula:C11H17NO
Molecular Weight:179.26

5856-63-3 Synthesis

5856-63-3
264 suppliers
$6.00/5g

100-52-7 Synthesis

100-52-7
944 suppliers
$21.30/2g

6257-49-4
21 suppliers
$53.00/250mg

Yield:6257-49-4 97%

Reaction Conditions:

Stage #1: (2R)-2-aminobutan-1-ol;benzaldehyde in methanol at 20; for 1 h;Inert atmosphere;
Stage #2: with sodium tetrahydroborate in methanol at 0 - 20; for 1.5 h;Inert atmosphere;

References:

Hillisch, Alexander;Gericke, Kersten M.;Allerheiligen, Swen;Roehrig, Susanne;Schaefer, Martina;Tersteegen, Adrian;Schulz, Simone;Lienau, Philip;Gnoth, Mark;Puetter, Vera;Hillig, Roman C.;Heitmeier, Stefan [Journal of Medicinal Chemistry,2020,vol. 63,# 21,p. 12574 - 12594] Location in patent:supporting information

5856-63-3 Synthesis

5856-63-3
264 suppliers
$6.00/5g

100-44-7 Synthesis