(R)-2-(diMethylaMino)-3-Methylbutanoic acid synthesis
1synthesis methods
- Product Name:(R)-2-(diMethylaMino)-3-Methylbutanoic acid
- CAS Number:899900-52-8
- Molecular formula:C7H15NO2
- Molecular Weight:145.2
Yield:899900-52-8 96%
Reaction Conditions:
with palladium 10% on activated carbon;hydrogen in water at 20; under 760.051 Torr; for 120 h;
References:
King, Amber M.;De Ryck, Marc;Kaminski, Rafal;Valade, Anne;Stables, James P.;Kohn, Harold [Journal of Medicinal Chemistry,2011,vol. 54,# 19,p. 6432 - 6442] Location in patent:supporting information; experimental part