(R)-2-(Methoxydiphenylmethyl)pyrrolidine synthesis
- Product Name:(R)-2-(Methoxydiphenylmethyl)pyrrolidine
- CAS Number:948595-05-9
- Molecular formula:C18H21NO
- Molecular Weight:267.37
1016-09-7
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948595-05-9
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Yield:-
Steps:
Multi-step reaction with 2 steps
1.1: N,N,N,N,-tetramethylethylenediamine; n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -40 °C / Inert atmosphere
1.2: 1 h / -78 °C / Inert atmosphere
2.1: hydrogenchloride / methanol / 4 h / 0 - 70 °C
2.2: 6 h / 20 °C
References:
Reddy, Arava Amaranadha;Prasad, Kavirayani R. [Journal of Organic Chemistry,2018,vol. 83,# 18,p. 10776 - 10785]