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ChemicalBook CAS DataBase List (R)-4-(1-AMINOETHYL)PHENOL

(R)-4-(1-AMINOETHYL)PHENOL synthesis

3synthesis methods
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Yield:> 99 % ee

Reaction Conditions:

Stage #1: α-methyl-p-hydroxybenzylaminewith (R)-amine dehydrogenase in dimethyl sulfoxide at 37; pH=8.5;Resolution of racemate;Microbiological reaction;Enzymatic reaction;
Stage #2: with (S)-ω-transaminase in dimethyl sulfoxide at 37; pH=9.5; for 24 h;Catalytic behavior;Resolution of racemate;Microbiological reaction;Enzymatic reaction;enantioselective reaction;

References:

Yoon, Sanghan;Patil, Mahesh D.;Sarak, Sharad;Jeon, Hyunwoo;Kim, Geon-Hee;Khobragade, Taresh P.;Sung, Sihyong;Yun, Hyungdon [ChemCatChem,2019,vol. 11,# 7,p. 1898 - 1902]

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