(R)-7-fluoro-2-Methyl-1,2,3,4-tetrahydroquinoline synthesis
1synthesis methods
- Product Name:(R)-7-fluoro-2-Methyl-1,2,3,4-tetrahydroquinoline
- CAS Number:1388106-07-7
- Molecular formula:C10H12FN
- Molecular Weight:165.21
Yield:> 99 % ee
Reaction Conditions:
with monoamine oxidase from Pseudomonas monteilii ZMU-T01 in aq. buffer at 37; pH=7.5;Resolution of racemate;enantioselective reaction;
References:
Deng, Guozhong;Wan, Nanwei;Qin, Lei;Cui, Baodong;An, Miao;Han, Wenyong;Chen, Yongzheng [ChemCatChem,2018,vol. 10,# 11,p. 2374 - 2377]