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ChemicalBook CAS DataBase List (R)-ChroMan-2-ylMethanaine
404337-71-9

(R)-ChroMan-2-ylMethanaine synthesis

9synthesis methods
(R)-3,4-dihydro-2H-chromene-2-carboxamide

437763-61-6
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(R)-ChroMan-2-ylMethanaine

404337-71-9
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Yield:404337-71-9 82%

Reaction Conditions:

with diborane in tetrahydrofuran;Inert atmosphere;Reflux;

References:

Marco, Isabel;Valhondo, Margarita;Martín-Fontecha, Mar;Vázquez-Villa, Henar;Del Río, Joaquín;Planas, Anna;Sagredo, Onintza;Ramos, José A.;Torrecillas, Iván R.;Pardo, Leonardo;Frechilla, Diana;Benhamú, Bellinda;López-Rodríguez, María L. [Journal of Medicinal Chemistry,2011,vol. 54,# 23,p. 7986 - 7999] Location in patent:experimental part