(R,R,R)-Aprepitant synthesis
- Product Name:(R,R,R)-Aprepitant
- CAS Number:1148113-53-4
- Molecular formula:C23H21F7N4O3
- Molecular Weight:534.43
252742-72-6
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![(2R,3R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine](/CAS/20150408/GIF/380499-06-9.gif)
380499-06-9
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1148113-53-4
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$504.12/5MG
Yield:1148113-53-4 99%
Reaction Conditions:
with potassium carbonate in water;N,N-dimethyl-formamide at 0;
References:
Gangula, Srinivas;Elati, Chandrashekhar R.;Mudunuru, Satish Varma;Nardela, Anitha;Dongamanti, Ashok;Bhattacharya, Apurba;Bandichhor, Rakeshwar [Synthetic Communications,2010,vol. 40,# 15,p. 2254 - 2268] Location in patent:experimental part