Ro 24-4736 synthesis
6synthesis methods
- Product Name:Ro 24-4736
- CAS Number:125030-71-9
- Molecular formula:C31H20ClN5OS
- Molecular Weight:546.04
![4-(2-Chlorophenyl)-2-iodo-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine](/CAS/20200119/GIF/67860-41-7.gif)
Yield:125030-71-9 76%
Reaction Conditions:
with copper(l) iodide;palladium diacetate;triethylamine;triphenylphosphine in N,N-dimethyl-formamide; for 72 h;Ambient temperature;
References:
Walser;Flynn;Mason;Crowley;Maresca;Yaremko;O'Donnell [Journal of Medicinal Chemistry,1991,vol. 34,# 3,p. 1209 - 1221]