Ronacaleret synthesis
- Product Name:Ronacaleret
- CAS Number:753449-67-1
- Molecular formula:C25H31F2NO4
- Molecular Weight:447.51
702687-43-2
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Yield:-
Steps:
Multi-step reaction with 4 steps
1: palladium diacetate; tris-(o-tolyl)phosphine; N-ethyl-N,N-diisopropylamine / 3.5 h / 115 °C / Inert atmosphere
2: sodium hydroxide / ethanol; water / 12 h / 20 °C
3: hydrogenchloride / diethyl ether; acetonitrile
4: 5 % Pd/CaCO3; hydrogen / acetic acid; ethyl acetate / 15 h
References:
US9227914,2016,B2
702687-42-1
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753449-67-1
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