ChemicalBook CAS DataBase List (S)-(-)-1-Amino-1-phenylpropaneHCl

(S)-(-)-1-Amino-1-phenylpropaneHCl synthesis

8synthesis methods

Product Name:(S)-(-)-1-Amino-1-phenylpropaneHCl
CAS Number:19146-52-2
Molecular formula:C9H13N.HCl
Molecular Weight:171.67

925-90-6 Synthesis

925-90-6
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$12.00/5ml

100-52-7 Synthesis

100-52-7
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$21.30/2g

19068-33-8
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19146-52-2
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Yield:19068-33-8 95 % Spectr.

Reaction Conditions:

Stage #1: benzaldehydewith titanium(IV) tetraethanolate;(S)-[5-Me-5-(SONH₂)hexyl]-modified polystyrene in tetrahydrofuran;
Stage #2: ethylmagnesium bromide in dichloromethane at -48;
Stage #3: with hydrogenchloride in dichloromethane;butan-1-ol;Title compound not separated from byproducts;

References:

Dragoli;Burdett;Ellman [Journal of the American Chemical Society,2001,vol. 123,# 41,p. 10127 - 10128]