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ChemicalBook CAS DataBase List (S)-1-CBZ-3-HYDROXYMETHYLPYRROLIDINE
124391-76-0

(S)-1-CBZ-3-HYDROXYMETHYLPYRROLIDINE synthesis

9synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: methanol / 100 °C
2.1: LiAlH4 / tetrahydrofuran / Heating
2.2: H2 / Pd(OH)2/C / methanol / 20 °C
2.3: K2CO3 / tetrahydrofuran; H2O / 0 °C

References:

Blanchet, Jérôme;Pouliquen, Mickael;Lasne, Marie-Claire;Rouden, Jacques [Tetrahedron Letters,2007,vol. 48,# 33,p. 5727 - 5730]

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