S-[2,2'-binaphthalene]-1,1'-diol synthesis

13synthesis methods

Product Name:S-[2,2'-binaphthalene]-1,1'-diol
CAS Number:122531-88-8
Molecular formula:C20H14O2
Molecular Weight:286.324

135-19-3 Synthesis

135-19-3
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Yield:122531-88-8 95%

Reaction Conditions:

with iron(III) chloride;dihydrogen peroxide in methanol;water at 70 - 75; for 1 h;Reagent/catalyst;Temperature;

Steps:

10 Example 5:

In a 250 mL four-necked flask, a thermometer, an electric stirrer, and a reflux condenser were added, and 9.5 g of methanol, 14.4 g of 2-naphthol, and 0.72 g of sodium dodecylbenzenesulfonate were added, and the mixture was heated to 70 ° C to dissolve. Then, 114.9 g of an aqueous solution of ferric chloride having a mass concentration of 23.5% and 2.83 g of hydrogen peroxide having a mass concentration of 30% were added in portions under heat retention conditions, and the reaction was kept at 75 ° C for 1 hour.The progress of the mixed solution was monitored, and when the 2-naphthol content was monitored by high performance liquid chromatography to be ≤ 3.0%, the reaction was stopped. Then, 12.0 g of toluene was added, and the reaction was further stirred at 70 ° C for 30 min, and the crystal was cooled, filtered, washed, and dried to obtain 12.87 g of 2,2'-binaphthol, the yield was 90.0%, and the product YI value (measured by a color difference meter). 3.5, HPLC result 99.0258%(Area%), all meet the requirements of electronic products.

References:

CN108083985,2018,A Location in patent:Paragraph 0039; 0044; 0047; 0050; 0051; 0054; 0056; 0058