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ChemicalBook CAS DataBase List (S)-(-)-2-AMINO-4-METHYL-1,1-DIPHENYL-1-PENTANOL
78603-97-1

(S)-(-)-2-AMINO-4-METHYL-1,1-DIPHENYL-1-PENTANOL synthesis

6synthesis methods
-

Yield:78603-97-1 100%

Reaction Conditions:

Stage #1: bromobenzenewith magnesium in diethyl ether at 40;Inert atmosphere;
Stage #2: methyl (L)-leucinate hydrochloride in diethyl ether at 0 - 20; for 15.5 h;

References:

Berkessel, Albrecht;Harnying, Wacharee;Duangdee, Nongnaphat;Neudoerfl, Joerg-M.;Groeger, Harald [Organic Process Research and Development,2012,vol. 16,# 1,p. 123 - 128] Location in patent:experimental part

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