(S)-2-Isopropyl-1,2,3,4-tetrahydroquinoxaline synthesis

Yield:1252875-58-3 98%

Reaction Conditions:

with {[IrH((S)-Difluorophos)]2(μ-Cl)3}+Cl-;hydrogen in toluene at 30; under 22502.3 Torr; for 20 h;Inert atmosphere;Autoclave;optical yield given as %ee;enantioselective reaction;

References:

Cartigny, Damien;Nagano, Takuto;Ayad, Tahar;Genet, Jean-Pierre;Ohshima, Takashi;Mashima, Kazushi;Ratovelomanana-Vidala, Virginie [Advanced Synthesis and Catalysis,2010,vol. 352,# 11-12,p. 1886 - 1891] Location in patent:supporting information; experimental part