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(S)-5-(HydroxyMethyl)-3,3-diMethylpyrrolidin-2-one synthesis

4synthesis methods
156088-45-8 Synthesis
(S)-3,3,6,6-TETRAMETHYLTETRAHYDROPYRROLO[1,2-C]OXAZOL-5(3H)-ONE

156088-45-8
16 suppliers
$107.00/0.25/ G

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Yield:156088-46-9 100%

Reaction Conditions:

with toluene-4-sulfonic acid in methanol; for 4 h;Heating;

References:

Davies, Stephen G.;Dixon, Darren J.;Doisneau, Gilles J.-M.;Prodger, Jeremy C.;Sanganee, Hitesh J. [Tetrahedron Asymmetry,2002,vol. 13,# 6,p. 647 - 658]