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(S)-5-oxo-2-Pyrrolidineacetic acid synthesis

6synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 95 percent / K2CO3 / 0.5 h / Ambient temperature
2: 64 percent / aq. NaOH / methanol / 18 h / Ambient temperature

References:

Nagao;Dai;Ochiai;Tsukagoshi;Fujita [Journal of Organic Chemistry,1990,vol. 55,# 4,p. 1148 - 1156]