ChemicalBook CAS DataBase List (S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one

(S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one synthesis

7synthesis methods

Product Name:(S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one
CAS Number:847926-88-9
Molecular formula:C14H12N2O
Molecular Weight:224.26

(S)-7-amino-5-(4-methoxy-benzyl)-5H,7H-dibenzo[b,d]azepin-6-one

847926-46-9
1 suppliers
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(S)-7-Amino-5H,7H-dibenzo[b,d]azepin-6-one

847926-88-9
15 suppliers
$95.00/1mg

Yield:847926-88-9 96%

Reaction Conditions:

with trifluorormethanesulfonic acid;trifluoroacetic acid in dichloromethane at 20; for 4 h;

Steps:

80.d

A solution of 0.55 g (1.6 mmol) (S)-7-amino-5-(4-methoxy-benzyl)-5H,7H-dibenzo[b,d]azepin-6-one, 3.74 ml (50 mmol) trifluoroacetic acid and 1.4 ml (16 mmol) trifluormethane sulfonic acid in 38 ml dichloromethane was stirred at room temperature for 4 hours. The solvent was distilled off and extraction with aqueous sodium bicarbonate solution/ethyl acetate followed by chromatography on silicagel with ethylacetate/methanol (100-95/0-5) yielded 0.35 g (96%) (S)-7-amino-5H,7H-dibenzo[b,d]azepin-6-one as orange solid; MS: m/e: 225.4 (M+H⁺).

References:

US2005/75327,2005,A1 Location in patent:Page/Page column 27

20011-90-9
34 suppliers
$120.50/50mg

847926-88-9
15 suppliers
$95.00/1mg

References

5- (4-methoxy-benzyl)-5H,7H-dibenzo[b,d]azepin-6-one

847926-44-7
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847926-88-9
15 suppliers
$95.00/1mg

References

7-amino-5-(4-methoxybenzyl)-5H dibenzo[b,d]azepin-6(7H)-one

847926-45-8
1 suppliers
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847926-88-9
15 suppliers
$95.00/1mg

References

[1,1'-Biphenyl]-2-acetonitrile, 2'-amino-

325141-76-2
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847926-88-9
15 suppliers
$95.00/1mg

References