S-AllylGlyEt HCl synthesis
- Product Name:S-AllylGlyEt HCl
- CAS Number:89105-35-1
- Molecular formula:C7H13NO2
- Molecular Weight:143.18
64-17-5
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Yield:89105-35-1 89%
Reaction Conditions:
with thionyl chloride at 0 - 20; for 16 h;Inert atmosphere;
Steps:
5.3 Step 3: (S)-Ethyl 2-aminopent-4-enoate (S5)
[0476] To a solution of Scheme 5-7 compound S4 (5 g, 43.5 mmol) in EtOH (70 mL) was added SOCI2 (15.52 g, 130.5 mmol) dropwisely at 0 °C. The reaction was stirred at room temperature for 16 h and concentrated. The residue was triturated with Et20 (60 mL) and filtered to afford the title compound (7 g, yield 89 %) as a white powder, which was directly used in the next reaction without further purification. LC/MS (ESI) m/z: 144 (M+H)+.
References:
WO2017/35405,2017,A1 Location in patent:Paragraph 0476
16338-48-0
241 suppliers
$11.00/250mg
89105-35-1
11 suppliers
inquiry