Silane, (5-bromo-1-pentynyl)trimethyl- synthesis
7synthesis methods
- Product Name:Silane, (5-bromo-1-pentynyl)trimethyl-
- CAS Number:66927-74-0
- Molecular formula:C8H15BrSi
- Molecular Weight:219.19
Yield:66927-74-0 738 mg
Reaction Conditions:
Stage #1: trimethylsilylacetylenewith n-butyllithium in hexane;
Stage #2: 1,3-dibromo-propanewith triphenylphosphine;tris(dibenzylideneacetone)dipalladium (0) in tetrahydrofuran;Heating;Kumada-Corriu reaction;
References:
Yang, Lian-Ming;Huang, Li-Fu;Luh, Tien-Yau [Organic Letters,2004,vol. 6,# 9,p. 1461 - 1463]