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ChemicalBook CAS DataBase List SIMVASTATIN, SODIUM SALT

SIMVASTATIN, SODIUM SALT synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: N-ethyl-N,N-diisopropylamine / Isopropyl acetate / 2.16 h / 2 - 25 °C
2.1: sodium hydroxide / water / 25 °C
2.2: 3407 / 0.08 h / 25 °C / Enzymatic reaction
2.3: 3407 / 25 °C / Enzymatic reaction

References:

Codexis, Inc.;Collier, Steven J.;Teo, Ee Ling;Sukumaran, Joly;Wilson, Robert J.;Xu, Junye US9399785, 2016, B2

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