![](/CAS/GIF/15484-44-3.gif)
Sodium 2-chloroethanesulfonate monohydrate synthesis
- Product Name:Sodium 2-chloroethanesulfonate monohydrate
- CAS Number:15484-44-3
- Molecular formula:C2H6ClNaO3S
- Molecular Weight:168.57
![1-Bromo-2-chloroethane](/CAS/GIF/107-04-0.gif)
107-04-0
269 suppliers
$9.00/1g
![Sodium 2-chloroethanesulfonate monohydrate](/CAS/GIF/15484-44-3.gif)
15484-44-3
299 suppliers
$10.00/25g
Yield:15484-44-3 92.7 %
Reaction Conditions:
with tetrabutyl-ammonium chloride;copper(l) chloride;sodium sulfite in water at 50;Reagent/catalyst;Temperature;Time;
Steps:
6-8; 10 Example 8
Add 440 ml of water to the three-necked flask, then add 0.8 mol of sodium sulfite, 0.08 mol of copper chloride, and 0.02 mol of tetrabutylammonium chloride.Heat to 50°C, then slowly add 4 mol of 1-bromo-2-chloroethane dropwise for 1 hour, and then continue to stir and react at 50°C for 0.5 hour, and the reaction ends.The reaction solution was slightly cooled to 40°C, allowed to stand and separated into layers, the 1-bromo-2-chloroethane in the lower layer was recovered, and the upper aqueous layer was evaporated under reduced pressure to obtain a slurry residue, and 500ml of methanol was added to the residue, Reflux for 0.5h and filter while hot to remove sodium chloride, cool the filtrate to 0°C for 2h, precipitate crystals from the filtrate, after filtration, use the filtrate as the mother liquor for dissolving the slurry residue, and dry the filter cake at 50°C to obtain the target The yield of the product 2-sodium chloroethylsulfonate is 92.7%, and the purity of chromatographic analysis is 99.5%.
References:
CN115448858,2022,A Location in patent:Paragraph 0062-0070; 0074-0086
![1,2-Dichloroethane](/CAS/GIF/107-06-2.gif)
107-06-2
406 suppliers
$14.00/25g
![Sodium 2-chloroethanesulfonate monohydrate](/CAS/GIF/15484-44-3.gif)
15484-44-3
299 suppliers
$10.00/25g
![1,2-Dichloroethane](/CAS/GIF/107-06-2.gif)
107-06-2
406 suppliers
$14.00/25g
![Sodium sulfite](/CAS/GIF/7757-83-7.gif)
7757-83-7
697 suppliers
$13.50/250G
![Sodium 2-chloroethanesulfonate monohydrate](/CAS/GIF/15484-44-3.gif)
15484-44-3
299 suppliers
$10.00/25g
![2-HYDROXYETHANE-1-SULFONYL CHLORIDE](/CAS/20180629/GIF/78303-70-5.gif)
78303-70-5
12 suppliers
inquiry
![Sodium isethionate](/CAS/GIF/1562-00-1.gif)
1562-00-1
385 suppliers
$5.00/25g
![Sodium ethylenesulphonate](/CAS/GIF/3039-83-6.gif)
3039-83-6
291 suppliers
$14.00/5g
![Sodium 2-chloroethanesulfonate monohydrate](/CAS/GIF/15484-44-3.gif)
15484-44-3
299 suppliers
$10.00/25g
![2-HYDROXYETHANE-1-SULFONYL CHLORIDE](/CAS/20180629/GIF/78303-70-5.gif)
78303-70-5
12 suppliers
inquiry
![Sodium isethionate](/CAS/GIF/1562-00-1.gif)
1562-00-1
385 suppliers
$5.00/25g
![Sodium 2-chloroethanesulfonate monohydrate](/CAS/GIF/15484-44-3.gif)
15484-44-3
299 suppliers
$10.00/25g