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ChemicalBook CAS DataBase List t-Butyl 4-chloro-2-fluorobenzoate

t-Butyl 4-chloro-2-fluorobenzoate synthesis

1synthesis methods
120120-26-5 Synthesis
TRIETHYL(TRIFLUOROMETHYL)SILANE

120120-26-5
98 suppliers
$14.00/250mg

Benzoic acid, 2-fluoro-4-(trifluoromethyl)-, 1,1-dimethylethyl ester

1240100-16-6
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Yield:1240100-16-6 72%

Reaction Conditions:

with potassium fluoride;dicyclohexyl-(2′,4′,6′-triisopropyl-3,6-dimethoxy-[1,1′-biphenyl]-2-yl)phosphine;bis(dibenzylideneacetone)-palladium(0) in 1,4-dioxane at 130;

References:

Cho, Eun Jin;Senecal, Todd D.;Kinzel, Tom;Zhang, Yong;Watson, Donald A.;Buchwald, Stephen L. [Science,2010,vol. 328,# 5986,p. 1679 - 1681] Location in patent:scheme or table

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