Tak-715 synthesis
- Product Name:Tak-715
- CAS Number:303162-79-0
- Molecular formula:C24H21N3OS
- Molecular Weight:399.51
90101-20-5
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$60.00/100mg
303162-79-0
112 suppliers
$65.00/5mg
Yield:-
Steps:
Multi-step reaction with 5 steps
1.1: BuLi / tetrahydrofuran; hexane / 0.5 h / 0 °C
1.2: 81 percent / tetrahydrofuran; hexane / -78 - 20 °C
2.1: 86 percent / Br2; AcOH / 3 h / 80 °C
3.1: 60 percent / dimethylformamide / 14 h / 20 °C
4.1: Et3N / tetrahydrofuran / 3 h / 20 °C
5.1: 59.8 g / HCl / tetrahydrofuran; H2O / 14 h / 40 °C
References:
Miwatashi, Seiji;Arikawa, Yasuyoshi;Kotani, Etsuo;Miyamoto, Maki;Naruo, Ken-Ichi;Kimura, Hiroyuki;Tanaka, Toshimasa;Asahi, Satoru;Ohkawa, Shigenori [Journal of Medicinal Chemistry,2005,vol. 48,# 19,p. 5966 - 5979]
303162-39-2
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303162-79-0
112 suppliers
$65.00/5mg
303162-37-0
1 suppliers
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303162-79-0
112 suppliers
$65.00/5mg
21384-43-0
4 suppliers
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303162-79-0
112 suppliers
$65.00/5mg
303162-39-2
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98-88-4
578 suppliers
$10.00/5g
303162-79-0
112 suppliers
$65.00/5mg