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Terbuprol synthesis

2synthesis methods
-

Yield:-

Reaction Conditions:

Stage #1: t-butyl glycidyl ether;sodium methylate in methanol at 70; for 0.5 h;
Stage #2: with water in methanol;Cooling with ice;

References:

Garcia, Jose I.;Garcia-Marin, Hector;Mayoral, Jose A.;Perez, Pascual [Green Chemistry,2010,vol. 12,# 3,p. 426 - 434] Location in patent:experimental part

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