tert-butyl (1R,2R)-2-aMinocyclopentylcarbaMate synthesis

2synthesis methods

Product Name:tert-butyl (1R,2R)-2-aMinocyclopentylcarbaMate
CAS Number:1016971-66-6
Molecular formula:C10H20N2O2
Molecular Weight:200.28

245115-25-7 Synthesis

(1S,2R)-Boc-2-amino-1-cyclopentanecarboxylic acid

245115-25-7
80 suppliers
$40.00/100 mg

tert-butyl (1R,2R)-2-aMinocyclopentylcarbaMate

1016971-66-6
34 suppliers
$118.00/100mg

Yield:-

Steps:

Multi-step reaction with 4 steps
1.1: Et₃N; ethyl chloroformate / tetrahydrofuran / 0.33 h / 0 °C
1.2: aq. NaN₃ / tetrahydrofuran / 0.33 h / 0 °C
2.1: benzene / 0.5 h / Heating
3.1: CuCl / dimethylformamide / 0.75 h / 20 °C
4.1: H₂ / Pd/C / methanol / 12 h / 2844.31 Torr

References:

Pokorski, Jonathan K.;Witschi, Mark A.;Purnell, Bethany L.;Appella, Daniel H. [Journal of the American Chemical Society,2004,vol. 126,# 46,p. 15067 - 15073]

benzyl tert-butyl (1R,2R)-cyclopentane-1,2-diyldicarbaMate

815645-30-8
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1016971-66-6
34 suppliers
$118.00/100mg

References