TERT-BUTYL-4-AMINOPHENYLACETATE synthesis
- Product Name:TERT-BUTYL-4-AMINOPHENYLACETATE
- CAS Number:174579-31-8
- Molecular formula:C12H17NO2
- Molecular Weight:207.27
29704-38-9
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174579-31-8
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Yield: 51%
Reaction Conditions:
with palladium 10% on activated carbon;hydrogen in methanol for 3 h;
Steps:
55.2 Tert-butyl 2- (4-aminophenyl) acetate
Compound 2- (4-nitrophenyl) t-butyl acetate 55b (5 g, 21 mmol) was dissolved in methanol (30 mL),Then 10% palladium on carbon (1 g) was added and stirred for 3 hours under a hydrogen atmosphere.After the reaction was completed, the filtrate was filtered, and the solvent was removed under reduced pressure.The target product tert-butyl 2- (4-aminophenyl) acetate 55c (2.25 g, yellow oil) was obtained in a yield of 51%.
References:
Beijing Nuochengjianhua Pharmaceutical Technology Co., Ltd.;Chen Xiangyang;Pang Yucheng CN110818641, 2020, A Location in patent:Paragraph 0700-0702; 0707-0710
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51656-70-3
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106-40-1
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174579-31-8
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$18.00/100mg
104-03-0
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$5.00/10g
174579-31-8
63 suppliers
$18.00/100mg