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Tetrazolo[1,5-a]pyridine-6-carboxylic acid synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: sulfuric acid / 0.5 h / 0 °C
1.2: 11.5 h / 0 - 20 °C
2.1: sodium azide; hydrogenchloride / ethanol; water / 24 h / 120 °C / Sealed tube

References:

Roy, Satyajit;Khatua, Hillol;Das, Sandip Kumar;Chattopadhyay, Buddhadeb [Angewandte Chemie - International Edition,2019,vol. 58,# 33,p. 11439 - 11443][Angew. Chem.,2019,vol. 131,# 33,p. 11561 - 11565]

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