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thiane-2-carbonitrile synthesis

6synthesis methods
70759-78-3 Synthesis
methyl tetrahydro-2H-thiopyran-2-carboxylate

70759-78-3
12 suppliers
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thiane-2-carbonitrile

146428-12-8
7 suppliers
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-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: ammonia / methanol / 120 h / Ambient temperature
2: polyphosphoric acid trimethylsilyl ester / benzene / 2 h / Heating

References:

Kataoka, Tadashi;Iwama, Tetsuo;Tsutsumi, Kazuhiro;Nakamura, Yoshihide;Matsumoto, Harutoshi;et al. [Journal of Chemical Research, Miniprint,1992,# 12,p. 3153 - 3194]