Thiocarbohydrazide synthesis
- Product Name:Thiocarbohydrazide
- CAS Number:2231-57-4
- Molecular formula:CH6N4S
- Molecular Weight:106.15
75-15-0
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$40.00/100 g
2231-57-4
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$31.00/5g
Yield:2231-57-4 98%
Reaction Conditions:
with hydrazine in water at 20; for 0.333333 h;Green chemistry;
Steps:
Typical experimental procedure for symmetrical thioureas derivatives
General procedure: To a 50 mL round bottom flask equipped with a magnetic stirrer, add carbon disulphide (5 mmol) and amine (10 mmol) in ice cold condition followed by addition of water (5 mL). Cork the flask. The reaction mixture was stirred vigorously at room temperature. The progress of the reaction was checked by TLC (10% MeOH: chloroform or EtOAc: hexane). After completion of reaction, solid was obtained by removal of water under reduced pressure on rotary evaporator while in some cases (Entry 7, 9, 10, 11 and 14, 15) the reaction mixture solidified when the reaction on completion. The obtained solid product was recrystallized with ethanol or washing with mixture EtOAc : hexane.
References:
Jangale, Asha D.;Kumavat, Priyanka P.;Wagh, Yogesh B.;Tayade, Yogesh A.;Mahulikar, Pramod P.;Dalal, Dipak S. [Synthetic Communications,2015,vol. 45,# 3,p. 376 - 385] Location in patent:supporting information
75-15-0
234 suppliers
$40.00/100 g
302-01-2
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$39.89/5g
2231-57-4
217 suppliers
$31.00/5g
471-32-9
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2231-57-4
217 suppliers
$31.00/5g
