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ChemicalBook CAS DataBase List Tr-PEG9

Tr-PEG9 synthesis

7synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 4 steps
1.1: triethylamine / dichloromethane / 1 h / 0 °C
2.1: potassium tert-butylate / tert-butyl alcohol / 0.5 h / Reflux
2.2: 13 h / Reflux
3.1: triethylamine / dichloromethane / 1 h / 0 °C
4.1: potassium tert-butylate / tert-butyl alcohol / 0.5 h / Reflux
4.2: 2 h / Reflux

References:

Kawamura, Shuhei;Ito, Yoshihiko;Hirokawa, Takatsugu;Hikiyama, Eriko;Yamada, Shizuo;Shuto, Satoshi [Journal of Medicinal Chemistry,2018,vol. 61,# 9,p. 4020 - 4029]