ChemicalBook CAS DataBase List TRANS-2-BUTENAL DIETHYL ACETAL

TRANS-2-BUTENAL DIETHYL ACETAL synthesis

5synthesis methods

Product Name:TRANS-2-BUTENAL DIETHYL ACETAL
CAS Number:63511-92-2
Molecular formula:C8H16O2
Molecular Weight:144.21

123-73-9
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$40.00/5g

122-51-0 Synthesis

122-51-0
485 suppliers
$10.00/5ml

63511-92-2
23 suppliers
$828.13/5ML

Yield:63511-92-2 89%

Reaction Conditions:

with ammonium nitrate in ethanol at 20; for 22 h;

Steps:

XXIX.A

Step A. (2E)-1,1-diethoxybut-2-ene Crotonaldehyde (23.64 mL, 285.35 mmol), triethyl orthoformate (57.02 mL, 342.42 mmol) and ammonium nitrate (2.28 g, 28.54 mmol) were combined in 60 mL EtOH. After 22 h at ambient temperature, the reaction was diluted with EtOAc (60 mL) and washed with saturated sodium bicarbonate solution (40 mL). The aqueous layer was back extracted with EtOAc (20 mL). The combined organics were washed with brine (40 mL), dried over Na₂SO₄, filtered and concentrated in vacuo to give 36.5 g (89%) of 1,1-diethoxybut-2-ene. 1H NMR (CDCl₃, 400 MHz) 5.84 (m, 1H); 5.54 (m, 1H); 4.82 (d, J=5.7 Hz, 1H); 3.64 (m, 2H); 3.49 (m, 2H); 1.73 (m, 3H); 1.21 (m, 6H).

References:

US2007/142634,2007,A1 Location in patent:Page/Page column 25