ChemicalBook CAS DataBase List UK 2A

UK 2A synthesis

8synthesis methods

Product Name:UK 2A
CAS Number:167173-85-5
Molecular formula:C26H30N2O9
Molecular Weight:514.52

2-Oxazolidinone, 4-(1-methylethyl)-3-(1-oxo-3-phenylpropyl)-, (4R)-

96837-44-4
0 suppliers
inquiry

167173-85-5
4 suppliers
inquiry

Yield:-

Steps:

Multi-step reaction with 12 steps
2: aq. H₂O₂, LiOH / 12 h / 25 °C
3: 89 percent / triphenylphosphine, DIAD / tetrahydrofuran / 0.67 h / 25 °C
4: 99 percent / imidazole / dimethylformamide / 17 h / 60 °C
5: 2,3-dichloro-5,6-dicyano-1,4-benzoquinone / CH₂Cl₂; H₂O / 0.5 h / 25 °C
6: DMAP, EDCI / CH₂Cl₂ / 2 h / 10 °C
7: 100 percent / H₂ / Pd(OH)2 / ethanol / 14 h / 25 °C / 3040 Torr
8: 87 percent / Ph₃P, DIAD / CH₂Cl₂ / 24 h / 25 °C
9: 100 percent / HF, pyridine / tetrahydrofuran / 72 h / Ambient temperature
10: 94 percent / pyridine / 5.5 h / 0 °C
11: 100 percent / trifluoroacetic acid / CH₂Cl₂ / 2 h / 25 °C
12: HOBt, EDCI*HCl, N-methylmorpholine / dimethylformamide / 10 h / 25 °C

References:

Shimano, Masanao;Kamei, Noriyuki;Shibata, Tetsuo;Inoguchi, Kiyoshi;Itoh, Nobuko;Ikari, Takashi;Senda, Hisato [Tetrahedron,1998,vol. 54,# 42,p. 12745 - 12774]

L-Arabinonic acid, 2,5-dideoxy-3-O-[(1,1-dimethylethyl)dimethylsilyl]-2-(phenylmethyl)-, phenylmethyl ester, ester with N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)-L-serine (9CI)

215798-03-1
0 suppliers
inquiry

167173-85-5
4 suppliers
inquiry

References

L-Arabinonic acid, 2,5-dideoxy-3-O-[(1,1-dimethylethyl)dimethylsilyl]-2-(phenylmethyl)-, phenylmethyl ester

210300-08-6
0 suppliers
inquiry

167173-85-5
4 suppliers
inquiry

References

3-Hydroxy-4-Methoxypyridine-2-carboxylic acid

210300-09-7
46 suppliers
$167.00/100mg

Propanoic acid, 2-methyl-, (3S,6S,7R,9R)-3-amino-6-methyl-4,9-dioxo-8-(phenylmethyl)-1,5-dioxonan-7-yl ester (9CI)

210300-07-5
0 suppliers
inquiry

167173-85-5
4 suppliers
inquiry

References

210300-15-5
2 suppliers
inquiry

167173-85-5
4 suppliers
inquiry

References