Urea, methoxy- synthesis

5synthesis methods

Product Name:Urea, methoxy-
CAS Number:3272-27-3
Molecular formula:C2H6N2O2
Molecular Weight:90.08

590-28-3 Synthesis

590-28-3
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$10.00/5g

593-56-6 Synthesis

593-56-6
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$8.00/100dtn(0.1g)

3272-27-3
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Yield:3272-27-3 93%

Reaction Conditions:

in water at 20; for 0.333333 h;

Steps:

O-Methylhydroxylaminehydrochloride

Acetophenone wasdistilled off from the mixture of acetophenone O-methyloxime (15 g)and 100 mL of conc. HCl (bath temperature 140°C) under atmospheric pressure. The residueafter distillation was evaporated to dryness under reduced pressure to afford 8.41 g (100 %) of O-methylhydroxylamine hydrochloride. The ¹HNMR data are identical to the previously reported.⁴ This procedure is general for a wide variety ofO-alkylhydroxylamines

References:

Kolosov, Maksim A.;Kulyk, Olesia G.;Al-Ogaili, Muataz J.K.;Orlov, Valeriy D. [Tetrahedron Letters,2015,vol. 56,# 32,art. no. 46433,p. 4666 - 4669] Location in patent:supporting information