Vanillyl butyl ether synthesis
- Product Name:Vanillyl butyl ether
- CAS Number:82654-98-6
- Molecular formula:C12H18O3
- Molecular Weight:210.27
498-00-0
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71-36-3
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82654-98-6
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$32.00/5G
Yield:82654-98-6 83%
Reaction Conditions:
with sulfated tungstate at 80; for 3 h;Green chemistry;chemoselective reaction;
Steps:
General procedure for sulphated-tungstate-mediated synthesis of 1-(butoxymethyl)-4-methoxybenzene (Table 3, entry 4)
General procedure: Sulfated tungstate (10 wt%) was added to a mixture of p-methoxybenzyl alcohol (1 g, 7.25 mmol) and n-butanol (1.34 g, 18.11 mmol), and the reaction mixture was stirred at 80 °C for 1 h. The progress of the reaction was monitored by thin-layer chromatography (TLC). After completion of the reaction, the reaction mixture was diluted with EtOAc (15 ml) and filtered to recover the catalyst. The organic layer was concentrated under reduced pressure, and the residue obtained was purified by chromatography on silica gel (60-120) with n-hexane-EtOAc (90:10) as eluent to get pure p-methoxybenzyl ether as a colorless oil.
References:
Katkar, Kamlesh V.;Veer, Sachin D.;Akamanchi, Krishnacharya G. [Synthetic Communications,2016,vol. 46,# 23,p. 1893 - 1901] Location in patent:supporting information
121-33-5
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$9.00/1g
71-36-3
1023 suppliers
$14.00/25mL
82654-98-6
302 suppliers
$32.00/5G
109-69-3
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121-33-5
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82654-98-6
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109-65-9
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$10.00/10g
121-33-5
1089 suppliers
$9.00/1g
82654-98-6
302 suppliers
$32.00/5G