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ChemicalBook CAS DataBase List ZILPATEROL

ZILPATEROL synthesis

1synthesis methods
92260-82-7 Synthesis
4,5-Dihydro-6-oxiMe-iMidazo[4,5,1-jk][1]benzazepine-2,6,7(1H)-trione

92260-82-7
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ZILPATEROL

117827-79-9
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Yield:-

Steps:

Multi-step reaction with 3 steps
1: hydrogen / methanol; N,N-dimethyl-formamide / 20 - 60 °C / 750.08 - 3750.38 Torr
2: potassium carbonate / 50 °C
3: sodium tetrahydroborate; methanol / 2 h / 10 - 40 °C

References:

Jiangsu Lingyun Pharmaceutical Co., Ltd.;Ling Qingyun;Bi Yaling;Yang Lingwei;Xiang Liangbin CN108752352, 2018, A

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