ChemicalBook >> CAS DataBase List >>Alpha-Lipoic Acid
Alpha-Lipoic Acid
- CAS No.
- 1077-28-7
- Chemical Name:
- Alpha-Lipoic Acid
- Synonyms
- ALA;THIOCTIC ACID;ALPHA-LIPOIC ACID;ALPHA-LIPOIC ACID;DL-THIOCTIC ACID;Thioctic acid CRS;A-LIPOIC ACID;alpha lipoic acid powder;DL-A-LIPOIC ACID;Alpha Acid Lipoic
- CBNumber:
- CB00128821
- Molecular Formula:
- C8H14O2S2
- Molecular Weight:
- 206.33
- MDL Number:
- MFCD00005474
- MOL File:
- 1077-28-7.mol
- MSDS File:
- SDS
Last updated:2024-06-07 09:09:32
| Melting point | 60-62 °C |
|---|---|
| Boiling point | 160-165 °C(lit.) |
| Density | 1.2888 (rough estimate) |
| refractive index | 1.5200 (estimate) |
| Flash point | 160-165°C |
| storage temp. | 2-8°C |
| solubility | ethanol: 50 mg/mL |
| form | Crystals or Crystalline Powder |
| pka | 4.75±0.10(Predicted) |
| color | Yellow |
| Water Solubility | 0.9 g/L (20 ºC) |
| Merck | 14,9326 |
| BRN | 81853 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | AGBQKNBQESQNJD-UHFFFAOYSA-N |
| LogP | 2.530 (est) |
| CAS DataBase Reference | 1077-28-7(CAS DataBase Reference) |
| FDA UNII | 73Y7P0K73Y |
| NIST Chemistry Reference | Dl-thioctic acid(1077-28-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H317-H319-H411 | |||||||||
| Precautionary statements | P261-P273-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-20/21/22 | |||||||||
| Safety Statements | 37/39-26-24/25-36-36/37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | JP1192000 | |||||||||
| HS Code | 29349990 | |||||||||
| NFPA 704 |
|
Alpha-Lipoic Acid price More Price(61)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 62320 | (±)-α-Lipoic acid ≥98.0% | 1077-28-7 | 5G | $112 | 2024-03-01 | Buy |
| Sigma-Aldrich | PHR2561 | Alpha Lipoic Acid | 1077-28-7 | 1G | $173 | 2024-03-01 | Buy |
| Sigma-Aldrich | 62320 | (±)-α-Lipoic acid ≥98.0% | 1077-28-7 | 25g | $286 | 2024-03-01 | Buy |
| Sigma-Aldrich | 437692 | α-Lipoic Acid - CAS 1077-28-7 - Calbiochem α-Lipoic Acid, CAS 1077-28-7 is an oxidized form with antioxidant properties. Reduces renal lipid peroxidation in rats with cisplatin n-induced nephrotoxicity. | 1077-28-7 | 5G | $111 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1368201 | Alpha Lipoic Acid United States Pharmacopeia (USP) Reference Standard | 1077-28-7 | 500mg | $394 | 2024-03-01 | Buy |
Alpha-Lipoic Acid Chemical Properties,Uses,Production
Biological Activity
Alpha-lipoic acid is found in every cell, where it helps turn glucose into energy. Antioxidants attack "free radicals," waste products created when the body turns food into energy. Free radicals cause harmful chemical reactions that can damage cells, making it harder for the body to fight infections. They also damage organs and tissues. In the body's cells, alpha-lipoic acid is changed into dihydrolipoic acid.
Side effects
Some people may experience some side effects, including:
Low blood sugar
Nausea
Rash (when using an ALA cream or ointment)
Vomiting
Since ALA is an acid, it may contribute to reflux.
Antioxidant
Alpha-lipoic acid (ALA) is a caprylic acid-derived antioxidant. The compound is synthesized in the mitochondria and is a cofactor in the enzymatic nutrient breakdown. It is a supplement for managing chronic diseases characterized by oxidative stress, notably diabetic neuropathy. It demonstrates promise in slowing the onset of metabolic syndrome through antioxidant properties. This supplement exhibits multifaceted features, functioning as an antioxidant by mitigating oxidative stress-induced damage linked to chronic metabolic disorders.
Food source
Alpha-lipoic acid can be eaten in foods, such as red meat, carrots, beets, spinach, broccoli, and potatoes. It is also available in supplements.
Alpha-Lipoic Acid Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 916)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shandong Luning Pharmaceutical Co., Ltd. | 0546-6491488 +8613305469775 | China | 40 | 58 | |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | info@konochemical.com | China | 2995 | 58 |
| Xi'an ZB Biotech Co.,Ltd | +8618591943808 | sales01@xazbbio.com | China | 816 | 58 |
| Guangzhou TongYi biochemistry technology Co.,LTD | +8613073028829 | mack@tongyon.com | China | 2996 | 58 |
| XI'AN TIANGUANGYUAN BIOTECH CO., LTD. | +86-029-86333380 18829239519 | sales06@tgybio.com | China | 935 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 50000 | 58 |
| Wuhan Quanjinci New Material Co.,Ltd. | +8615271838296 | kyra@quanjinci.com | China | 1534 | 58 |
| Chongqing Zhihe Biopharmaceutical Co., Ltd. | +86-18580541567 +86-17782035140 | sales@zhswyy.com | China | 326 | 58 |
| BINBO BIOLOGICAL CO.,LTD | +8618629063126 | info@binbobiological.com | China | 346 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | info@fortunachem.com | China | 6000 | 58 |
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Related Qustion
- Q:Which foods include α-Lipoic Acid?
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- Jun 5，2024
View Lastest Price from Alpha-Lipoic Acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-11-30 | Alpha Lipoic Acid
1077-28-7
|
US $80.00-70.00 / kg | 100kg | 99%HPLC,USP Standard | 8000KGs | ZhenYiBio Technology Inc | |
 |
2023-03-24 | Alpha Lipoic Acid
7516-48-5
|
US $0.00 / g | 1g | 99.9% | 200kgs | Hebei Bonster Technology Co.,Limited |
-
- Alpha Lipoic Acid
1077-28-7
- US $80.00-70.00 / kg
- 99%HPLC,USP Standard
- ZhenYiBio Technology Inc
-
- Alpha Lipoic Acid
7516-48-5
- US $0.00 / g
- 99.9%
- Hebei Bonster Technology Co.,Limited
1077-28-7(Alpha-Lipoic Acid)Related Search:
5 MG PNPP SUBSTRATE TABLETS REAGENT GR
(1)-ALPHA-LIPOIC ACID
DL-α-Lipoic acidUSP,
99.0-101.0% (Assay)
5-(1,2)Dithiolan-3-yl-pentanoic acid for synthesis
TIMTEC-BB SBB003484
THIOOCTIC ACID
dl-1,2-Dithiolane3-valericacid
DL-6-Thioctic acid
dl-6-Thiocticacid
Thioctic acid, dl-form
DL-PROTOGEN A
DL-1,2-DITHIOLANE-3-PENTANOIC ACID
DITHIOOCTANIC ACID
DL-6,8-DITHIOOCTANOIC ACID
DL-6,8-THIOCTIC ACID OXIDIZED FORM
DL-6,8-THIOOCTIC ACID
LIP(S2)
LIPOIC ACID, DL-ALPHA-
5-(1,2)DITHIOLAN-3-YL-PENTANOIC ACID
6,8-DITHIOOCTANOIC ACID
(+/-)-ALPHA-LIPOIC ACID
ALPHA-LIPONIC ACID
(+/-)-1,2-DITHIOLANE-3-VALERIC ACID
1,2-DITHIOLANE-3-VALERIC ACID
DL-α-Lipoic acid
(-ALPHA-LIPOIC ACID (-ALPHA-LIPOIC ACID
Dl-ThiocticAcid,Oxidized
R(+)-Alpha-LipoicAcid99%
DL-Thioctic acid, 98+% 5GR
LIPOIC ACID, DL-ALPHA-(AS)
DL-a-Lipoic acid USP
DL-ThioCLic Acid
alpha-lipoic acid (CAS )
DL-α-Lipoic acid
(+/-)-alpha-Lipoic acid >=98.0%
(+-)-2-dithiolane-3-pentanoicacid
(+-)-2-dithiolane-3-valericacid
(+/-)-2-dithiolane-3-pentanoicacid
1,2-Dithiolane-3-pentanoicacid,(+-)-(9CI)
DL-Thioctic acid, 98+%
(RS)-a-Lipoic Acid
NSC 628502
NSC 90788
rac a-Lipoic Acid
Alpha-Thioctic
LIPOICACID,REAGENT
A-THIOCTIC ACID
（Low Solvent Residue）
α-Lipic acid
(RS)-Lipoic acid
1,2-Dithiolane-3-valeric acid, (+-)- (8CI)
a-Liponic acid
α-Lipic acid（Low Solvent Residue）
2-Dithiolane-3-valericacid,(+-)-1
DL-1,2-Dithiolan-3-valeriansaeure
DL-1,2-Dithiolane 3-valeric acid
DL-ALPHA-LIPOIC ACID (DL THIOCTIC ACID)
Alpha Lipoic Acid ( or DL-Thioctic Acid )