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Colecalciferol

Colecalciferol structure

CAS No.: 67-97-0

Chemical Name:: Colecalciferol

Synonyms: CHOLECALCIFEROL;VITAMIN D;COLECALCIFEROL;Vitamin D3 Crystal;VITAMINE D3;CALCIOL;Manufacturer;Cholecalciferol CRS;Cholecalciferol (Vitamin D3);Deparal

CBNumber:: CB00129316

Molecular Formula:: C27H44O
Lewis structure

Molecular Weight:: 384.64

MDL Number:: MFCD00078131

MOL File:: 67-97-0.mol

MSDS File:: SDS

Last updated:2024-05-22 11:23:49

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Colecalciferol Properties

Melting point	83-86 °C(lit.)
alpha	105 º (c=0.8, EtOH 25 ºC)
Boiling point	451.27°C (rough estimate)
Density	0.9717 (rough estimate)
vapor pressure	2.0 x l0^-6 Pa (20 °C, est.)
refractive index	1.5100 (estimate)
Flash point	14 °C
storage temp.	-20°C
solubility	Practically insoluble in water, freely soluble in ethanol (96 per cent), soluble in trimethylpentane and in fatty oils. It is sensitive to air, heat and light. Solutions in solvents without an antioxidant are unstable and are to be used immediately. A reversible isomerisation to pre-cholecalciferol takes place in solution, depending on temperature and time. The activity is due to both compounds.
pka	14.74±0.20(Predicted)
form	powder
color	White
Odor	odorless
Water Solubility	<0.1 g/L (20 ºC)
Sensitive	Air & Light Sensitive
Merck	14,10019
BRN	2339331
Stability	Light Sensitive, Temperature Sensitive
InChIKey	QYSXJUFSXHHAJI-YRZJJWOYSA-N
LogP	9.085 (est)
Substances Added to Food (formerly EAFUS)	VITAMIN D-3
SCOGS (Select Committee on GRAS Substances)	Vitamin D3 (cholecalciferol)
FDA 21 CFR	310.545
CAS DataBase Reference	67-97-0(CAS DataBase Reference)
EWG's Food Scores	2-5
FDA UNII	1C6V77QF41
NCI Dictionary of Cancer Terms	cholecalciferol
NCI Drug Dictionary	cholecalciferol
NIST Chemistry Reference	Cholecalciferol(67-97-0)
EPA Substance Registry System	Cholecalciferol (67-97-0)

Pharmacokinetic data

Protein binding	50-80%
Excreted unchanged in urine	Minimal
Biological half-life	50 days

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06,GHS08

Signal word

Danger

Hazard statements

H300+H310+H330-H372

Precautionary statements

P260-P262-P280-P302+P352+P310-P304+P340+P310-P314

Hazard Codes

Xn,T

Risk Statements

26-24/25 -48/25

Safety Statements

28-45-36/37

WGK Germany

RTECS

VS2900000

8-10-23

TSCA

Yes

HS Code

29362990

Toxicity

LD50 oral in rat: 42mg/kg

NFPA 704

	1
		1

Colecalciferol price More Price(62)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	V-025	Vitamin D3 solution 1?mg/mL in ethanol, ampule of 1?mL, certified reference material, Cerilliant?	67-97-0	1mL	$99	2024-03-01	Buy
Sigma-Aldrich	740292	Vitamin D3 solution 100μg/mL in ethanol, 97% (CP)	67-97-0	1ml	$200	2024-03-01	Buy
Sigma-Aldrich	47763	Cholecalciferol (D3) analytical standard	67-97-0	100mg	$34	2024-03-01	Buy
Sigma-Aldrich	1131009	Cholecalciferol United States Pharmacopeia (USP) Reference Standard	67-97-0	5x30mg	$457	2024-03-01	Buy
Sigma-Aldrich	BP787	Colecalciferol British Pharmacopoeia (BP) Reference Standard	67-97-0	500MG	$252	2023-06-20	Buy

Product number	Packaging	Price	Buy
V-025	1mL	$99	Buy
740292	1ml	$200	Buy
47763	100mg	$34	Buy
1131009	5x30mg	$457	Buy
BP787	500MG	$252	Buy

Colecalciferol Chemical Properties,Uses,Production

Description

Colecalciferol is a form of Vitamin D. It helps you get more calcium and phosphorus from your food and reduces the elimination of calcium from your kidneys.

Uses

Colecalciferol is a dietary supplement used to treat vitamin D deficiency. It is also used with calcium to maintain bone strength.

Side effects

Common side effects of Colecalciferol include: stomach (gastrointestinal) pain, feeling sick (nausea), headache, cough, constipation, dizziness, chest tightness, and fatigue. Serious side effects may include frequent urination, swelling of any part of the body, high fever and severe pain on one side of the body or one side of the lower back (an early sign of kidney stones), vomiting, pain in the bones or joints, or irregularities in the heart rhythm. Taking too much cholecalciferol over a long period of time can lead to skin rashes and hypercalcaemia, stomach pains, weakening of the bones and damage to the kidneys and heart. Some patients may also experience symptoms of a severe allergic reaction, with tightness in the throat, difficulty swallowing, sudden swelling of the lips, mouth, throat or tongue, and difficulty breathing.

Colecalciferol Preparation Products And Raw materials

Raw materials

Silica glass Cyclohexane PASSION FLOWER OIL 7-Dehydrocholesterol

Preparation Products

COD LIVER OIL 7,8-Epoxy-vitamin D3 (1R,3S,Z)-5-((E)-2-((1S,3aS,7aS)-1-((S)-2-Hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol

Colecalciferol Suppliers

Global( 866)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Leading Chemical and Trading Co.,Ltd	+8615669938129	sales@leadingchemical.com	China	130	58
Hu Bei Jiutian Bio-medical Technology CO.,Ltd	027-88013699 17354350817	Ryan@jiutian-bio.com	China	7433	58
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	6011	58
Hangzhou ICH Biofarm Co., Ltd	+86-0571-28186870; +undefined8613073685410	sales@ichemie.com	China	985	58
Wuhan Marco Pharmaceutical Technology Co., Ltd.	+86-86-18572802410 +8618572802410	sales@marcopht.com	China	55	58
Nantong Guangyuan Chemicl Co,Ltd	+undefined17712220823	admin@guyunchem.com	China	616	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	19368	58
airuikechemical co., ltd.	+undefined86-15315557071	sales01@airuikechemical.com	China	994	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	+8618740459177	sarah@tnjone.com	China	1142	58
Ouhuang Engineering Materials (Hubei) Co., Ltd	+8617702722807	admin@hbouhuang.com	China	3001	58

Supplier	Advantage
Leading Chemical and Trading Co.,Ltd	58
Hu Bei Jiutian Bio-medical Technology CO.,Ltd	58
Hebei Yanxi Chemical Co., Ltd.	58
Hangzhou ICH Biofarm Co., Ltd	58
Wuhan Marco Pharmaceutical Technology Co., Ltd.	58
Nantong Guangyuan Chemicl Co,Ltd	58
Henan Fengda Chemical Co., Ltd	58
airuikechemical co., ltd.	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	58
Ouhuang Engineering Materials (Hubei) Co., Ltd	58

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View Lastest Price from Colecalciferol manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2023-08-21	Sodium tetraborate pentahydrate 12179-04-3		1kg	99%	100tons	Anhui Ruihan Technology Co., Ltd

Sodium tetraborate pentahydrate
12179-04-3
99%
Anhui Ruihan Technology Co., Ltd

Vitamin D3 Spectrum

Vitamin D3(67-97-0)¹HNMR Vitamin D3(67-97-0)IR1 Vitamin D3(67-97-0)Raman

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Vitamin D3 solution Vitamin D3-d3 Cholecalciferol (6,19,19-d3) Cholecalciferol d6 10-Secocholesta-5,7,10(19)-trien- (5Z,7E,3S)-9,10-Secocholesta-5,7,10(19)-trien-3-ol 3Z-[2E-[(1R,3aS,7aR)-1S-[1R,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-cyclohexanol (+)-VITAMIN D/3, CRYSTALLINE, 99+% CHOLECALCIFEROL, PH EUR CHOLECALCIFEROL CRYSTALLINE CHOLECALCIFEROL, USP VITAMIN D3 99+% VitaminD3(Cholecalciferol40000Iu) VitaminD3MedicalGrade VitaminD2MedicalGrade VitaminD3CrystalPowder(40,000,000Iu) Cholecalciferol/VitamineD3 VitaminD3U.S.P. VitaminD/VitaminD3 cholecalciferol,d3 d3-vicotrat D3-Vigantol Delsterol duphafrald31000 Ebivit Micro-dee neodohyfrald3 Provitina rampage Ricketon Trivitan VidDe-3-hydrosol 5,7,10(19)-CHOLESTATRIEN-3BETA-OL-9,10-SECO Cholecalciferol, USP Grade 9,10-Secocholesta-5,7,19(19)-trien-3-OL-(3B,5Z,7E)-choleciferol, USP Grade vitamin D3 ~40000 U/mg CHOLECALCIFEROL, PHARMA Vitamin D₃ colecalciferol, (+)-5,7-cholestadien-3в-ol CHOLECALCIFEROL,CRYSTAL,USP 3-[2-[7a-methyl-1-(6-methylheptan-2-yl)-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexan-1-ol DEHYDROCHOLESTEROL, 7-(RG) 1,3-Cyclohexanediol, 4-methylene-5-[(2E)-[(1S,3aS,7aS)-octahydro-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,3S,5Z)- (9CI) 1,3-Cyclohexanediol, 4-methylene-5-[2-[octahydro-1-[1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, [1S-[1a(R*),3ab,4E(1S*,3R*,5Z),7aa]]- 1a,25-Dihydroxy-22-oxavitamin D3 22-Oxa-1,25-dihydroxyvitamin D3 22-Oxa-1a,25-dihydroxyvitamin D3 22-Oxacalcitriol MC 1275 OCT (steroid) Oxarol Cholecaciferol 3b-Hydroxy-5,7-Cholestadien 5,7-Cholestadien-3b-Ol CHOLECALCIFEROL (D3) 100MG NEAT Cyclohexanol, 3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, (1S,3Z)- Vitamin d3, 99+%, crystalline Vitamin D3, crystalline 9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3-ol VITAMIN D3(CHOLECALCIFEROL)(USP)(P)