ChemicalBook >> CAS DataBase List >>Thioguanine
Thioguanine
- CAS No.
- 154-42-7
- Chemical Name:
- Thioguanine
- Synonyms
- THIOGUANINE;tioguanine;6-tg;2-AMINO-6-PURINETHIOL;lanvis;6-MERCAPTOGUANINE;2-AMINO-6-MERCAPTOPURINE;2-Amino-3,7-dihydropurine-6-thione;2-Amino-3,7-dihydro-6H-purine-6-thione;6H-Purine-6-thione, 2-amino-1,9-dihydro-
- CBNumber:
- CB00129710
- Molecular Formula:
- C5H5N5S
- Molecular Weight:
- 167.19
- MDL Number:
- MFCD00233553
- MOL File:
- 154-42-7.mol
- MSDS File:
- SDS
Last updated:2023-09-22 14:52:15
| Melting point | ≥300 °C(lit.) |
|---|---|
| Density | 1.483 (estimate) |
| refractive index | 1.5605 (estimate) |
| storage temp. | 2-8°C |
| solubility | Practically insoluble in water and in ethanol (96%). It dissolves in dilute solutions of alkali hydroxides. |
| form | lyophilized powder |
| pka | pKa 8.22 (Uncertain) |
| Boiling point | 555.4±42.0 °C(Predicted) |
| color | Yellow to green |
| Water Solubility | soluble |
| Merck | 14,9337 |
| BRN | 157765 |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMF may be stored at -20°C for up to 1 month. |
| CAS DataBase Reference | 154-42-7(CAS DataBase Reference) |
| NCI Dictionary of Cancer Terms | Tabloid; thioguanine |
| FDA UNII | WIX31ZPX66 |
| NCI Drug Dictionary | Tabloid |
| ATC code | L01BB03 |
| Proposition 65 List | Thioguanine |
| EPA Substance Registry System | Thioguanine (154-42-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P301+P310 | |||||||||
| Hazard Codes | T,Xi | |||||||||
| Risk Statements | 25-23/24/25 | |||||||||
| Safety Statements | 28-36/37/39-45-28A | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UP0740000 | |||||||||
| F | 13 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29335990 | |||||||||
| Toxicity | LD50 oral in mouse: 160mg/kg | |||||||||
| NFPA 704 |
|
Thioguanine price More Price(60)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR3250 | Thioguanine pharmaceutical secondary standard, certified reference material | 154-42-7 | 500MG | $201 | 2024-03-01 | Buy |
| Sigma-Aldrich | BP878 | Tioguanine British Pharmacopoeia (BP) Reference Standard | 154-42-7 | 100MG | $257 | 2024-03-01 | Buy |
| Sigma-Aldrich | A4660 | 6-Thioguanine Hybri-Max , 50 ×, γ-irradiated, lyophilized powder, BioXtra, suitable for hybridoma | 154-42-7 | 2.5mg | $26.7 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1660000 | Thioguanine United States Pharmacopeia (USP) Reference Standard | 154-42-7 | 200mg | $164.8 | 2024-03-01 | Buy |
| TCI Chemical | T0212 | 6-Thioguanine >95.0%(HPLC) | 154-42-7 | 1g | $94 | 2024-03-01 | Buy |
Thioguanine Chemical Properties,Uses,Production
Description
Thioguanine is used to treat acute myeloid leukemia (AML; a type of cancer that begins in the white blood cells). Thioguanine is in a class of medications known as purine analogs. It works by slowing or stopping the growth of cancer cells in your body.
Uses
Thioguanine is an antineoplastic anti-metabolite used in the treatment of several forms of leukemia including acute nonlymphocytic leukemia. Anti-metabolites masquerade as purine or pyrimidine - which become the building blocks of DNA. They prevent these substances becoming incorporated in to DNA during the "S" phase (of the cell cycle), stopping normal development and division.
Side effects
Nausea, vomiting, loss of appetite, and mouth sores may occur. Tell your doctor right away if you have any serious side effects, including: joint pain/swelling, black stools, vomit that looks like coffee grounds, symptoms of liver disease (such as nausea/vomiting that doesn't stop, stomach/abdominal pain, yellowing eyes/skin, dark urine). This medication may decrease bone marrow function, an effect that may lead to a low number of blood cells such as red cells, white cells, and platelets. This effect can cause anemia, decrease your body's ability to fight an infection, or cause easy bruising/bleeding.
Thioguanine Preparation Products And Raw materials
Raw materials
1of5
Preparation Products
Global( 347)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 6011 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5909 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
View Lastest Price from Thioguanine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-09-06 | 6-Thioguanine
154-42-7
|
US $0.00 / KG | 1KG | 99% | 500000kg | Hebei Guanlang Biotechnology Co., Ltd. | |
 |
2023-03-06 | 6-Thioguanine
154-42-7
|
US $10.70 / g/Bag | 10g | 99% | 10000kg | Hebei Guanlang Biotechnology Co,.LTD | |
 |
2023-01-14 | 6-Thioguanine
154-42-7
|
US $0.00 / kg | 1kg | 98%min | 1000kg | WUHAN FORTUNA CHEMICAL CO., LTD |
-
- 6-Thioguanine
154-42-7
- US $0.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.
-
- 6-Thioguanine
154-42-7
- US $10.70 / g/Bag
- 99%
- Hebei Guanlang Biotechnology Co,.LTD
-
- 6-Thioguanine
154-42-7
- US $0.00 / kg
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
154-42-7(Thioguanine)Related Search:
Ancitabine
6-Methylthioguanine
6-Thioguanosine hydrate
1,9-DIHYDRO-6H-PURINE-6-THIONE
6-N-HEPTYLMERCAPTOPURINE
2-Amino-6-mercaptopurine-13C2,15N
6,8-DIHYDROXY-2-METHYLMERCAPTOPURINE
6-(Methylthio)purine
6-thioinosine-5'-triphosphate
8-AZA-6-HYDROXY-2-MERCAPTOPURINE
1of4
2-Amino-1,7(9)-dihydro-purine-6-thione
2-amino-6-mercaptopurine (50X)*gamma-irradiated C
2-amino-6-mercaptopurine crystalline
2-Amino-6-purinethiol (6-Thioguanine)
2-AMINO-6-MERCAPTOPURINE (50X)GAMMA-IRRA DIATED CEL
Tioguanine(Thioguanine)
6-Thioguanine,~97%
6-THIOGUANIDE
2-AMINO-6-THIOLPURINE
2-amino-6-purinethio
6-THIOGUANINE 97% (HPLC)
2-Thioguanine
Guanine, t
purine antimetabolite: antimetabolite: inhibits nucleic acid replication
6H-Purine-6-thione, 2-amino-1,7-dihydro-
6-THIOGUANINE
2-amino-1,7-dihydro-6h-purin-6-thion
2-amino-1,7-dihydro-6h-purine-6-thion
2-aminopurine-6(1h)-thione
2-amino-purine-6(1h)-thion
2-Amino-6-mercaptopurine, 2-Amino-6-purinethiol
5'-ribonucleotide
dibutyryl cyclic AMP calcium salt
complex coenzyme
2-Amino-9H-purine-6(1H)-thione
2-Amino-6-purinethiol ,98%
6-THIOGUANINE (6SG)
2-Amino-6-purinethiol,95%
Thioguanine (200 mg)
6-TG/Thioguanine
Thioguanine API
2-Amino-6-mercaptopurine
6-Mercaptoguanine
2-amino-1,9-dihydro-6H-purine-6-thione
2-Amino-1,7-dihydro-6H-purin-6-thion [Czech]
2-Amino-6-merkaptopurin [Czech]
2-Aminopurin-6-thiol [Czech]
2-amino-1,7-dihydro-6h-purine-6-thione
2-amino-6-merkaptopurin
2-amino-6-mp
2-aminopurin-6-thiol
2-aMino-1H-purine-6(7H)-thione
2-aMino-3H-purine-6(7H)-thione
2-amino-purine-6-thio
2-aminopurine-6-thiol
6-mercapto-2-aminopurine
bw5071
nsc-752
purine-b-thiol,2-amino
tabloid
thio-guanin
tioguanin
wellcomeu3b
2-Amino-9H-purine-6-thiol
2-amino-6,7-dihydro-3H-purine-6-thione
6-Thioguanine>
6-Thioguanine (Solution)
Mercaptopurine Impurity 6
6-Thioguanine USP/EP/BP