alminoprofen
- CAS No.
- 39718-89-3
- Chemical Name:
- alminoprofen
- Synonyms
- EB 382;Minalfen;Minalfene;alminoprofen;Alminoprofene;Alminoprofeno;rac AlMinoprofen;alminoprofen USP/EP/BP;ALMINOPROFEN(FORR&DONLY);Alminoprofene [inn-french]
- CBNumber:
- CB7885929
- Molecular Formula:
- C13H17NO2
- Molecular Weight:
- 219.28
- MDL Number:
- MFCD00866084
- MOL File:
- 39718-89-3.mol
| Melting point | 107° |
|---|---|
| Boiling point | 360.1°C (rough estimate) |
| Density | 1.0697 (rough estimate) |
| refractive index | 1.5100 (estimate) |
| storage temp. | -20°C Freezer |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 4.86±0.50(Predicted) |
| color | Light Brown |
| FDA UNII | 0255AHR9GJ |
| ATC code | M01AE16 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| Toxicity | LD50 orally in mice: 2400 mg/kg (Dumaitre) |
alminoprofen price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | A575150 | racAlminoprofen | 39718-89-3 | 1g | $790 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0003395 | ALMINOPROFEN 95.00% | 39718-89-3 | 1G | $1575 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0003395 | ALMINOPROFEN 95.00% | 39718-89-3 | 2.5G | $2255 | 2021-12-16 | Buy |
| ChemScene | CS-0009220 | Alminoprofen 99.35% | 39718-89-3 | 100mg | $275 | 2021-12-16 | Buy |
| ChemScene | CS-0009220 | Alminoprofen 99.35% | 39718-89-3 | 250mg | $450 | 2021-12-16 | Buy |
alminoprofen Chemical Properties,Uses,Production
Description
Alminoprofen is an arylpropionic acid analgesic/antiinflammatory agent indicated for the short term management of dental, traumatic and postpartum pain.
Originator
Labs. Dr. E. Bouchara (France)
Uses
Alminoprofen is a nonsteroidal antiinflammatory drugs (NSAID) of the phenylpropionic acid class. Alminoprofen maybe a useful therapeutic option in the management of immune dysfunction in rheumatoid ar thritis.
Definition
ChEBI: A substituted aniline that is ibuprofen in which the isobutyl group is replaced by a (2-methylprop-2-en-1-yl)amino group. A non-steroidal anti-inflammatory drug, it is used for treatment of inflammatory and rheumatic disorders.
Manufacturing Process
Methyl 2-(p-aminophenyl)propionate:
Methyl 2-(p-nitrophenyl)acrylate (52 g) is hydrogenated in ethanol (500 ml) in
the presence of 5% palladium-over-charcoal, while maintaining the
temperature at +5°C. The theoretical amount of hydrogen is taken up within
one hour. After separation of the catalyst and concentration to dryness, the
resulting material gives methyl 2-(p-aminophenyl)proprionate which
crystallizes: MP: = 40°-43°C.
Methyl 2-(p-methallylaminophenyl)propionate hydrochloride:
A mixture of methyl 2-(p-aminophenyl)propionate (44.75 g), methallyl
chloride (34 g) and pyridine (30 ml) in isopropanol (400 ml) is boiled during
30 hours. The solvent is removed in vacuo and the residue is taken up into
water and ether. After separation, the organic phase is washed repeatedly
with water, after which it is dried and concentrated in vacuo. The resulting oil
is fractionally distilled in vacuo (0.1 mm Hg; 5 g of oil essentially consisting of
methyl 2-(p-aminophenyl)propionate are collected at 115°-120°C; 30 g of oil
consisting of a mixture of mono- (80%) and disubstituted (20%) amines is
collected at 128°-130°C. This oil is used to prepare the hydrochloride, which
is recrystallized from ethyl acetate, to give white crystals (22.7 g) melting at 115°C. Saponification in the cold methanolic hydroxide gives the desired 2-(4-
(methallylamino)phenyl)propionic acid (alminoprofen). MP: 120°C.
brand name
MINALFENE
Therapeutic Function
Analgesic, Antiinflammatory
alminoprofen Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569265 +86-18612256290 | 1056@dideu.com | China | 3082 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 27945 | 58 |
| Huadong Medicine (Xi'an)Bodyguard Pharmaceutical Co.,Ltd. | +86-029-86185165 +8618629664246 | guoyuan@eastchinapharm.com | China | 1615 | 58 |
| Aromsyn Co., Ltd. | +86-0571-85585865 +8613336024896 | CB@aromsyn.com | China | 19185 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 50002 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33350 | 58 |
View Lastest Price from alminoprofen manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-07-20 | alminoprofen
39718-89-3
|
US $1.00-1.00 / KG | 1g | 99% | 50tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2021-06-10 | alminoprofen USP/EP/BP
39718-89-3
|
US $1.10 / g | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2021-01-06 | alminoprofen
39718-89-3
|
US $8.00 / KG | 1g | Min98% HPLC/gc | g/kg/ton | Career Henan Chemica Co |
-
- alminoprofen
39718-89-3
- US $1.00-1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- alminoprofen USP/EP/BP
39718-89-3
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
-
- alminoprofen
39718-89-3
- US $8.00 / KG
- Min98% HPLC/gc
- Career Henan Chemica Co