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5-FLUORO-1,3-DIMETHYLURACIL

CAS No.
3013-92-1
Chemical Name:
5-FLUORO-1,3-DIMETHYLURACIL
Synonyms
Fluorouracil-001;Fluorouracil Impurity 34;1,3-dimethyl-5-fluorouracil;5-FLUORO-1,3-DIMETHYLURACIL;5-Fluoro-1,3-dimethyluracil 99%;5-fluoro-1,3-dimethylpyrimidine-2,4-dione;5-fluoro-1,3-diMethylpyriMidine-2,4(1H,3H)-dione;2,4(1H,3H)-Pyrimidinedione,5-fluoro-1,3-dimethyl-;1,3-Dimethyl-5-fluorouracil, 2,4-Dihydroxy-1,3-dimethyl-5-fluoropyrimidine
CBNumber:
CB8116404
Molecular Formula:
C6H7FN2O2
Molecular Weight:
158.13
MDL Number:
MFCD00192176
MOL File:
3013-92-1.mol
Last updated:2023-07-09 08:28:05

5-FLUORO-1,3-DIMETHYLURACIL Properties

Melting point 132-134 °C(lit.)
Boiling point 182.5±50.0 °C(Predicted)
Density 1.37±0.1 g/cm3(Predicted)
pka -4.07±0.40(Predicted)
BRN 880396

SAFETY

Risk and Safety Statements

Safety Statements  22-24/25
WGK Germany  3

5-FLUORO-1,3-DIMETHYLURACIL price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 406864 5-Fluoro-1,3-dimethyluracil 99% 3013-92-1 10g $151 2023-06-20 Buy
AK Scientific 1409AQ 5-Fluoro-1,3-dimethyluracil 3013-92-1 10g $212 2021-12-16 Buy
American Custom Chemicals Corporation NUC0002048 5-FLUORO-1,3-DIMETHYLURACIL 95.00% 3013-92-1 10G $1219.42 2021-12-16 Buy
Product number Packaging Price Buy
406864 10g $151 Buy
1409AQ 10g $212 Buy
NUC0002048 10G $1219.42 Buy

5-FLUORO-1,3-DIMETHYLURACIL Chemical Properties,Uses,Production

Uses

5-Fluoro-1,3-dimethyluracil may be used as starting material in the following processes:

  • Regioselective synthesis of tetrahydronaphthocyclobuta[1,2-d]pyrimidinediones.
  • To synthesize 5-bis(ethoxycarbonyl)methyl-1,3-dimethyluracil.
  • To synthesize new highly conjugated propenylidene derivatives via aromatic Paterno-Buchi type cycloaddition with 1-methoxynaphthalene.

Synthesis Reference(s)

Tetrahedron, 46, p. 3093, 1990 DOI: 10.1016/S0040-4020(01)88400-3

General Description

Oxidation of 5-fluoro-1,3-dimethyluracil (5-FDMU) with m-chloroperbenzoic acid has been described. It is reported as antineoplastic drug. On photoirradiation, 5-fluoro-1,3-dimethyluracil yields the trans-anti cyclobutane dimer and the cis-syn cyclobutane dimer. UV irradiation of 5-FDMU and naphthalene in a protic medium affords 5-(1-naphthyl)uracil, while in aprotic media it undergoes stereoselective 1,4-cycloaddition reaction to give a barrelene derivative. The thermochemical parameters of 5-FDMU has been determined. It reacts with substituted benzenes in the presence of trifluoroacetic acid to generate 5-aryl-1,3-dimethyluracils via photosubstitution.

67-56-1
874-14-6
3013-92-1
Synthesis of 5-FLUORO-1,3-DIMETHYLURACIL from Methanol and 1,3-Dimethyluracil

5-FLUORO-1,3-DIMETHYLURACIL Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 23)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-81138252 +86-18789408387 1057@dideu.com China 2628 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131980 58
Chemwill Asia Co.,Ltd. 86-21-51086038 chemwill_asia@126.com CHINA 23931 58
Shanghai Hanhong Scientific Co.,Ltd. 021-021-64543801 13764082696 2355241799@qq.com China 42982 64
Syntechem Co.,Ltd info@syntechem.com China 12990 57
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Shandong Chengchuang Blue Sea Pharmaceutical Technology Co., Ltd. 0531-58897130 15508676053 drug_impurity@sdcclh.com China 1828 58
Ningbo Zeyu Chemical Technology Co., Ltd 15066123231 15066123231 2278736577@qq.com China 509 58

View Lastest Price from 5-FLUORO-1,3-DIMETHYLURACIL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Fluorouracil-001  pictures 2020-05-15 Fluorouracil-001
3013-92-1
US $1.00 / KG 1KG 99% 20T Shaanxi Dideu Medichem Co. Ltd
1,3-Dimethyl-5-fluorouracil, 2,4-Dihydroxy-1,3-dimethyl-5-fluoropyrimidine 5-fluoro-1,3-diMethylpyriMidine-2,4(1H,3H)-dione 5-FLUORO-1,3-DIMETHYLURACIL 1,3-dimethyl-5-fluorouracil 2,4(1H,3H)-Pyrimidinedione,5-fluoro-1,3-dimethyl- Fluorouracil-001 5-Fluoro-1,3-dimethyluracil 99% 5-fluoro-1,3-dimethylpyrimidine-2,4-dione Fluorouracil Impurity 34 3013-92-1 Building Blocks Heterocyclic Building Blocks Pyrimidines