1,4-フェニレン ジイソチオシアナート 化学特性,用途語,生産方法
外観
白色~ほとんど白色, 結晶~結晶性粉末
溶解性
N,N-ジメチルホルムアミドに溶けるが、水にほとんど溶けない。
用途
アミノ酸配列分析用、二価性試薬。
化学的特性
off-white to yellow to beige-grey crystalline
使用
Reagent for solid-phase sequencing.
一般的な説明
Odorless colorless crystals. Melting point 132°C.
反応プロフィール
1,4-PHENYLENE DIISOTHIOCYANATE reacts readily with amines [Noller]. These reactions may generate significant amounts of heat . Emits very toxic fumes of nitrogen oxides and sulfur oxides when heated to decomposition [EPA, 1998].
健康ハザード
1,4-PHENYLENE DIISOTHIOCYANATE is highly toxic if ingested. It is a central nervous system and gastrointestinal toxin in humans.
火災危険
When heated to decomposition, 1,4-PHENYLENE DIISOTHIOCYANATE emits very toxic fumes of nitrogen oxides and sulfur oxides.
安全性プロファイル
Poison by ingestion and intraperitoneal routes. Human systemic effects by ingestion: hallucinations, nausea. When heated to decomposition it emits very toxic fumes of NOx,CN,and SOx.See also THIOCYANATES
職業ばく露
Those engaged in the manufacture,
formulation and application of this anthelmintic
compound.
Incompatibilities: In general, keep away from strong oxidizers,
moisture, strong acids, strong bases. This is a thiocyanate
compound. Violent reactions may occur upon contact
with chlorates (potassium chlorate, sodium chlorate),
nitrates, nitric acid; organic peroxides.
輸送方法
UN2811 Toxic solids, organic, n.o.s., Hazard
Class: 6.1; Labels: 6.1—Poisonous materials, Technical
Name Required.
純化方法
Purify bitoscanate by recrystallisation from AcOH, pet ether (b 40-60o), Me2CO or aqueous Me2CO. [van der Kerk et al. Recl Trav Chim Pays-Bas 74 1262 1955, Leiber & Slutkin J Org Chem 27 2214 1962, Beilstein 13 IV 174.]
不和合性
Incompatible with oxidizers (chlorates,
nitrates, peroxides, permanganates, perchlorates, chlorine,
bromine, fluorine, etc.); contact may cause fires or explosions.
Keep away from alkaline materials, strong bases,
strong acids, oxoacids, epoxides.
1,4-フェニレン ジイソチオシアナート 上流と下流の製品情報
原材料
準備製品