2,2-ビス(4-クロロフェニル)-1,1-ジクロロエチレン 化学特性,用途語,生産方法
外観
白色～ほとんど白色粉末～結晶
用途
農薬DDT代謝物
化学的特性
white crystalline powder
使用
Military product; chemical research. Degradation product of p,p′-DDT.
定義
ChEBI: A chlorophenylethylene that is ethylene substituted by two 4-chlorophenyl groups at position 1 and two chlorine atoms at position 2.
一般的な説明
White crystalline solid or white powder.
空気と水の反応
Insoluble in water.
反応プロフィール
4,4'-DDE is sensitive to exposure to light. 4,4'-DDE is incompatible with strong oxidizing agents and strong bases. Oxidation is catalyzed by UV radiation.
健康ハザード
A derivative of DDT; structurally and toxicproperties are similar to those of DDT;however, the acute effects are somewhatmilder; moderately toxic by ingestion; ateratogenic substance; adequate evidence ofcarcinogenicity in experimental animals
LD50 oral (rat): 880 mg/kg
LD50 oral (mouse): 700 mg/kg.
火災危険
Flash point data for 4,4'-DDE are not available. 4,4'-DDE is probably combustible.
安全性プロファイル
Suspected carcinogen withexperimental carcinogenic and neoplastigenic data. Poisonby ingestion. Experimental reproductive effects. Mutationdata reported. An insecticide. When heated todecomposition it emits very toxic fumes of Cl-.
環境運命予測
Biological. In four successive 7-day incubation periods, p,p′-DDE (5 and 10 mg/L) was recalcitrant to degradation in a settled domestic wastewater inoculum (Tabak et al.,1981).
Photolytic. When an aqueous solution of p,p′-DDE (0.004uM) in natural water samples
collected from California and Hawaii was irradiated (maximum λ= 240 nm) for 120
hours, 62% was photooxidized to p,p′-dichlorobenzophenone (Ross and Crosby, 1985).
When p,p′-DDE in water was irradiated at 313 nm, a quantum yield of 0.3 was
achieved. A photolysis half-life of 0.9 days in summer and 6.1 days in winter by direct
sunlight at 40° latitude was observed. Photolysis products included DDMU (yield 20%),
o-chl
When p,p′-DDE in a methanol solvent was photolyzed at 260 nm, a dichloro-benzophenone,
a dichlorobiphenyl, DDMU and 3,6-dichlorofluorenone (yield 10%) formed
as the major products (Plimmer et al., 1970).
Chemical/Physical. May degrade to bis(chlorophenyl)acetic acid (DDA) and hydrochloric
acid in water (Verschueren, 1983) or oxidize to p,p′-dichlorobenzophenone using
UV light as a catalyst (U.S. Department of Health and Human Services, 1989).
純化方法
Crystallise DDE from MeOH or EtOH and dry it in vacuo. The purity is checked by TLC. [G.tzi & Stammbach Helv Chim Acta 28 569 1946, Beilstein 5 H 639, 5 III1891.] POSSIBLE CARCINOGEN.
2,2-ビス(4-クロロフェニル)-1,1-ジクロロエチレン 上流と下流の製品情報
原材料
準備製品