2,3-디아미노벤조산

2,3-디아미노벤조산
2,3-디아미노벤조산 구조식 이미지
카스 번호:
603-81-6
한글명:
2,3-디아미노벤조산
동의어(한글):
2,3-디아미노벤조산
상품명:
2,3-Diaminobenzoic acid
동의어(영문):
3-Diaminobenzoic acid;2,3-Diaminobenzonicacid;2,3-DIAMINOBENZOIC ACID;Benzoic acid, 2,3-diamino-;2,3-bis(azanyl)benzoic acid;3-carboxy-1,2-diaminobenzene;2,3-diaMinobenzoic acid hydrochloride
CBNumber:
CB5194337
분자식:
C7H8N2O2
포뮬러 무게:
152.15
MOL 파일:
603-81-6.mol

2,3-디아미노벤조산 속성

녹는점
198-204 °C
끓는 점
274.61°C (rough estimate)
밀도
1.2804 (rough estimate)
굴절률
1.5200 (estimate)
저장 조건
Keep in dark place,Inert atmosphere,Room temperature
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
5.10±0.10(Predicted)
색상
갈색에서 진한 갈색까지
CAS 데이터베이스
603-81-6(CAS DataBase Reference)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xi,Xn
위험 카페고리 넘버 22-36
안전지침서 26
위험 등급 IRRITANT
HS 번호 29224999
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H302 삼키면 유해함 급성 독성 물질 - 경구 구분 4 경고 GHS hazard pictograms P264, P270, P301+P312, P330, P501
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P271 옥외 또는 환기가 잘 되는 곳에서만 취급하시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.

2,3-디아미노벤조산 C화학적 특성, 용도, 생산

용도

2,3-Diaminobenzoic acid (23DBA) is an important organic reagent mainly used in scientific research and laboratory experiments. 23DBA can undergo polycondensation with terephthalic acid dichloro anhydride[1]. 23DBA isomer is also used in the study of luminescence mechanism of red luminescent carbon dots (RCDs)[2]. In addition, 2,3-Diaminobenzoic acid also possesses antioxidant properties that help reduce the formation of free radicals in the body. It is also used as a chelating agent that effectively binds to metal ions and prevents them from forming insoluble complexes.

Synthesis

2,3-Diaminobenzoic acid is synthesised using 3-nitroanthranilic acid as a raw material by chemical reaction. The specific synthesis steps are as follows:
2-amino-3-nitrobenzoic acid (9.36 g, 51.4 mmol) was dissolved in MeOH (100 mL) and there was added 10% Pd/C (2.0g). The reaction was stirred under H2-atmosphere (ambient pressure) until absorption ceased. The reaction was filtered through a pad of Celite and the filtrate was evaporated under reduced pressure. The product was purified by flash chromatography (CH2Cl2/MeOH 5:1) and the collected fractions were evaporated to give 2,3-Diaminobenzoic acid (5.40 g, 69%) as a dark brown solid. mp. 199 °C dec. (Litt4. 201 °C dec.). 1H NMR (300 MHz, DMSO-d6) δ 7.09 (dd, J = 8.0, 1.5 Hz, 1H), 6.67 (dd, J = 7.4, 1.5 Hz, 1H), 6.34 (dd, J = 8.0, 7.4 Hz, 2H), 6.32 (br s, 4H). 13C NMR (75 MHz, DMSO-d6) δ 170.5, 139.6, 135.6, 119.4, 117.0, 114.9, 110.3.
2,3-Diaminobenzoic acid synthesis

2,3-디아미노벤조산 준비 용품 및 원자재

원자재

준비 용품


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