6-플루오로-4-(트리플루오로메틸)-2(1H)-퀴놀리논

6-플루오로-4-(트리플루오로메틸)-2(1H)-퀴놀리논
6-플루오로-4-(트리플루오로메틸)-2(1H)-퀴놀리논 구조식 이미지
카스 번호:
328956-08-7
한글명:
6-플루오로-4-(트리플루오로메틸)-2(1H)-퀴놀리논
동의어(한글):
6-플루오로-4-(트리플루오로메틸)-2(1H)-퀴놀리논
상품명:
6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone
동의어(영문):
6-Fluoro-4-(trifluoromethyl)quinolin-2-ol;6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone;6-fluoro-4-(trifluoromethyl)-1H-quinolin-2-one;6-Fluoro-4-(trifluoroMethyl)quinolin-2(1H)-one;6-Fluoro-4-(trifluoromethyl)quinolin-2-ol ,97%;2(1H)-Quinolinone, 6-fluoro-4-(trifluoromethyl)-;6-Fluoro-2-hydroxy-4-(trifluoroMethyl)quinoline, 97%
CBNumber:
CB92128695
분자식:
C10H5F4NO
포뮬러 무게:
231.15
MOL 파일:
328956-08-7.mol

6-플루오로-4-(트리플루오로메틸)-2(1H)-퀴놀리논 속성

녹는점
252-253 °C (decomp)(Solv: ethanol (64-17-5))
끓는 점
282 ºC
밀도
1.468
인화점
124 ºC
저장 조건
2-8°C
산도 계수 (pKa)
9.33±0.70(Predicted)
InChI
InChI=1S/C10H5F4NO/c11-5-1-2-8-6(3-5)7(10(12,13)14)4-9(16)15-8/h1-4H,(H,15,16)
InChIKey
WUFRBOSKPZUGIS-UHFFFAOYSA-N
SMILES
N1C2=C(C=C(F)C=C2)C(C(F)(F)F)=CC1=O

안전

위험 카페고리 넘버 36/37/38
안전지침서 26-36/37/39
HS 번호 29334900

6-플루오로-4-(트리플루오로메틸)-2(1H)-퀴놀리논 C화학적 특성, 용도, 생산

화학적 성질

White solid

개요

As a quinoline derivative, 6-Fluoro-4-hydroxy-2-(trifluoromethyl)quinoline is substituted with trifluoromethyl, hydroxyl, and fluoride groups. In particular, 6-Fluoro-4-hydroxy-2-(trifluoromethyl)quinoline can exist in a tautomeric form, known as quinolone, where the hydroxy group becomes a ketone and the imine changes to an amine. This compound is a precursor for synthesizing thioquinolines, which are used to develop non-cytotoxic, potent and selective antitubercular agents. The thiolation reaction is carried out using phosphorus pentasulfide in pyridine.

6-플루오로-4-(트리플루오로메틸)-2(1H)-퀴놀리논 준비 용품 및 원자재

원자재

준비 용품


6-플루오로-4-(트리플루오로메틸)-2(1H)-퀴놀리논 공급 업체

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