| Company Name: |
Zhuhai Anzhe Biotechnology Co,Ltd.
|
| Tel: |
13169972583 |
| Email: |
244176264@qq.com |
| Products Intro: |
Cas:51-21-8
ProductName:fluorouracil
Purity: 95%HPLC | Package: 25mg;50mg;100mg
|
| Company Name: |
Foshan Treasure Biotechnology Co., Ltd
|
| Tel: |
0757-85921206 18520245316 |
| Email: |
2329783215@qq.com |
| Products Intro: |
Cas:51-21-8
ProductName:Fluorouracil
Purity: 99% HPLC | Package: 20mg；50mg；100mg；1g
|
- Fluorouracil
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- $9.00 / 10g
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2024-05-11
- CAS:51-21-8
- Min. Order: 10g
- Purity: 99%
- Supply Ability: 10 tons
- Fluorouracil
-
- $100.00 / 1kg
-
2024-04-22
- CAS:51-21-8
- Min. Order: 1kg
- Purity: 99.93%
- Supply Ability: 1000kg per week
- Fluorouracil
-
- $0.00 / 1g
-
2024-03-12
- CAS:51-21-8
- Min. Order: 1g
- Purity: 98% HPLC
- Supply Ability: 100kg
|
| Product Name: | Fluorouracil | | Synonyms: | 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-;2,4-dioxo-5-fluoropyrimidine;3h)-pyrimidinedione,5-fluoro-4(1h;5-faracil;fluoro-uracile;fluoro-uracilo;fluorouracilum;Fluracilum | | CAS: | 51-21-8 | | MF: | C4H3FN2O2 | | MW: | 130.08 | | EINECS: | 200-085-6 | | Product Categories: | Inhibitors;Anticancer;Nucleotides and Nucleosides;Biochemistry;Chemical Reagents for Pharmacology Research;Nucleobases and their analogs;Nucleosides, Nucleotides & Related Reagents;Nucleic acids;Bases & Related Reagents;Pharmaceutical Raw Materials;PYRIMIDINE;Heterocycles;Pyridines, Pyrimidines, Purines and Pteredines;Phenylacetic acid;Tegafur Carmofur;Metabolites & Impurities, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals;CARAC;Inhibitor;Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical intermediate;Antitumour;API's;Nucleotides;51-21-8 | | Mol File: | 51-21-8.mol |  |
| | Fluorouracil Chemical Properties |
| Melting point | 282-286 °C (dec.) (lit.) | | Boiling point | 190-200°C/0.1mmHg | | density | 1.4593 (estimate) | | storage temp. | 2-8°C | | solubility | H2O: 10 mg/mL, clear | | form | powder | | pka | pKa 8.0±0.1 (H2O) (Uncertain);3.0±0.1(H2O) (Uncertain) | | color | white | | PH | 4.3-5.3 (10g/l, H2O, 20℃) | | Water Solubility | 12.2 g/L 20 ºC | | Sensitive | Air Sensitive | | Merck | 14,4181 | | BRN | 127172 | | Stability: | Stable. Light sensitive. Combustible. Incompatible with strong oxidizing agents, strong bases. | | InChIKey | GHASVSINZRGABV-UHFFFAOYSA-N | | CAS DataBase Reference | 51-21-8(CAS DataBase Reference) | | IARC | 3 (Vol. 26, Sup 7) 1987 | | NIST Chemistry Reference | 2,4-Pyrimidinedione, 5-fluoro-(51-21-8) | | EPA Substance Registry System | 5-Fluorouracil (51-21-8) |
| | Fluorouracil Usage And Synthesis |
| Description | Fluorouracil (5-FU) is a skin cream or solution that treats skin cancer. It’s a chemotherapy agent that destroys cancer cells. | | Mechanism of action | Fluorouracil is part of a group of chemotherapy drugs known as anti metabolites. Anti metabolites are similar to normal body molecules but they have a slightly different structure.
These differences mean that anti metabolites stop cancer cells working properly. They stop the cells making and repairing DNA. Cancer cells need to make and repair DNA so that they can grow and multiply. | | Side effects | Common side effects occurring in more than 10% of individuals may include: 1. Increased risk of infection: This is caused by a decrease in white blood cells and can manifest as symptoms such as fluctuating temperature, muscle aches, headaches, chills, and a general feeling of being unwell. Additional symptoms may vary depending on the location of the infection. In some cases, infections can be severe, so it is important to seek urgent medical advice if an infection is suspected. 2. Pallor and breathlessness: A reduction in red blood cells, known as anaemia, may lead to breathlessness and a pale appearance. 3. Elevated risk of bleeding and bruising: A decrease in platelet count can result in a higher likelihood of bleeding and bruising. This may present as nosebleeds, bleeding gums, or the development of small red spots or bruises (petechiae) on the skin. | | Precautions | Fluorouracil is only for use on the skin. Follow the directions on the prescription label. Wash hands before and after use. Wash affected area and gently pat dry. To apply this medicine use a cotton-tipped applicator, or use gloves if applying with fingertips. If applied with unprotected fingertips, it is very important to wash your hands well after you apply this medicine. Avoid applying to the eyes, nose, or mouth. Apply enough medicine to cover the affected area. You can cover the area with a light gauze dressing, but do not use tight or air-tight dressings. Finish the full course prescribed by your doctor or health care professional, even if you think your condition is better. Do not stop taking except on the advice of your doctor or health care professional.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. |
| | Fluorouracil Preparation Products And Raw materials |
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