- Terbinafine HCl
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- $150.00 / 1kg
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2023-05-30
- CAS:78628-80-5
- Min. Order: 1kg
- Purity: 99.9%
- Supply Ability: 10000MT
- Terbinafine HCL
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- $10.00 / 1KG
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2021-08-31
- CAS:78628-80-5
- Min. Order: 1KG
- Purity: 99.99%
- Supply Ability: 20 tons/month
- Terbinafine HCl
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- $1.00 / 1kg
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2019-05-22
- CAS:78628-80-5
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 500KG
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| Product Name: | Terbinafine Hcl | | Synonyms: | Terbinafine hydrochloride, >=98%;Terbinafinehydrochloride(GMP);terbinafine hydrochloride, N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine hydrochloride;1-Naphthalenemethanamine, N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-methyl-, hydrochloride (1:1);Terbinafine Hydrochioride Tablets;n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalenemethanamin(e)-1-naphthalenemethanaminmon;TRANS-N-(6,6-DIMETHYL-2-HEPTEN-4-YNYL)-N-METHYL-1-NAPHTHYLMETHYLAMINE HYDROCHLORIDE;(e)-n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalenemethanamine monohydrochloride | | CAS: | 78628-80-5 | | MF: | C21H26ClN | | MW: | 327.89 | | EINECS: | 616-640-4 | | Product Categories: | Acetylenes;Antifungals for Research and Experimental Use;Biochemistry;Functionalized Acetylenes;Terbinafine;Antifungal;APIs;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;LAMISIL;API;78628-80-5 | | Mol File: | 78628-80-5.mol |  |
| | Terbinafine Hcl Chemical Properties |
| Melting point | 204-208°C | | storage temp. | 15-25°C | | solubility | methanol: soluble50mg/mL | | form | powder | | color | white | | Merck | 14,9156 | | BCS Class | 1 | | InChI | InChI=1S/C21H25N.ClH/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19;/h5-7,9-14H,16-17H2,1-4H3;1H/b9-5+; | | InChIKey | BWMISRWJRUSYEX-SZKNIZGXSA-N | | SMILES | C12C=CC=CC1=CC=CC=2CN(C)C/C=C/C#CC(C)(C)C.Cl | | CAS DataBase Reference | 78628-80-5(CAS DataBase Reference) |
| Hazard Codes | Xi,N | | Risk Statements | 36/37/38-50/53 | | Safety Statements | 26-36/37/39-61-60 | | RIDADR | UN 3077 9/PG 3 | | WGK Germany | 3 | | RTECS | QJ8600100 | | HS Code | 29214990 | | Toxicity | LD50 in mice, rats (mg/kg): 4000, 4000 orally; 393, 213 i.v. (Ganzinger) |
| | Terbinafine Hcl Usage And Synthesis |
| Description | Terbinafine Hcl is a prescription-only medication that is used to treat fungal infections on the skin and nails that are caused by trichophyton. Patients diagnosed with athlete’s foot, jock itch and ringworm use this medication to relieve their symptoms including irritation and burning. Terbinafine Hcl works by reducing the growth of fungi on the skin and nails. | | Biological Activity | Terbinafine Hcl is a hydrochloride obtained by reaction of terbinafine with one molar equivalent of hydrogen chloride. It has a role as an EC 1.14.13.132 (squalene monooxygenase) inhibitor and a P450 inhibitor. It is a hydrochloride and an allylamine antifungal drug. It contains a terbinafine(1+). | | Side effects | This common side effect of terbinafine Hcl:
Peeling or itching skin;
Rash;
Headache;
Diarrhoea;
Feeling or being sick (nausea or vomiting);
A smaller appetite than usual;
Losing your sense of taste;
Stomach ache;
Indigestion;
Muscle or joint pain;
Feeling dizzy;
Problems with your eyesight. |
| | Terbinafine Hcl Preparation Products And Raw materials |
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