| Company Name: |
Lynnchem
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86-(0)29-85992781 17792393971 |
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info@lynnchem.com |
| Products Intro: |
Product Name:OPHIOBOLIN B
CAS:5601-74-1
Purity:>95% by HPLC Package:1mg;5mg
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| | OPHIOBOLIN B Basic information |
| Product Name: | OPHIOBOLIN B | | Synonyms: | OPHIOBOLIN B;3,14-Dihydroxy-5-oxoophiobola-7,19-dien-25-al;Cochliobolin B;Cochliobolin B, Zizanin B, Ophiobolsin A;Dicyclopenta[a,d]cyclooctene-4-carboxaldehyde, 7-[(1S)-1,5-dimethyl-4-hexen-1-yl]-1,2,3,3a,6,6a,7,8,9,9a,10,10a-dodecahydro-1,7-dihydroxy-1,9a-dimethyl-3-oxo-, (1R,3aS,6aR,7S,9aR,10aS)-;Ophiobolin B (Cochliobolin B) | | CAS: | 5601-74-1 | | MF: | C25H38O4 | | MW: | 402.57 | | EINECS: | | | Product Categories: | | | Mol File: | 5601-74-1.mol |  |
| | OPHIOBOLIN B Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble | | form | White to off-white solid. |
| | OPHIOBOLIN B Usage And Synthesis |
| Uses | Ophiobolin B is a fungal phytotoxin and inhibits calmodulin (a protein involved in calcium regulation). Ophiobolin B also exhibit antibacterial and antitumor activities. | | Uses | Calmodulin is a calcium-sensing protein that regulates a wide array of proteins involved in diverse cellular functions. Ophiobolin B is a sesterterpenoid fungal phytotoxin that binds and irreversibly antagonizes calmodulin, producing cytotoxic and antimicrobial effects. It induces apoptosis in chronic lymphocytic leukemia cells with an LC50 value of 2 nM and in different zygomycetes with MIC values ranging from 25-50 μg/ml.[Cayman Chemical] | | Uses | Ophiobolin B is a minor member of a class of phytotoxic metabolites produced by Bipolaris and other genera of plant pathogenic fungi. Ophiobolin B acts by inhibiting calmodulin action in calcium regulation. |
| | OPHIOBOLIN B Preparation Products And Raw materials |
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