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| | 3',4'-DIHYDROXYPROPIOPHENONE Basic information |
| Product Name: | 3',4'-DIHYDROXYPROPIOPHENONE | | Synonyms: | 1-(3,4-dihydroxyphenyl)-1-propanon;3’,4’-dihydroxy-propiophenon;3',4'-DIHYDROXYPROPIOPHENONE;3,4-DIHYDROXYPROPIOPHENONE;3',4'-Dihydroxypropiophenone,98%;1-Propanone,1-(3,4-dihydroxyphenyl)-;1-(3,4-dihydroxyphenyl)propan-1-one;1-(3,4-Dihydroxyphenyl)-1-propanone | | CAS: | 7451-98-1 | | MF: | C9H10O3 | | MW: | 166.17 | | EINECS: | | | Product Categories: | Aromatic Propiophenones (substituted) | | Mol File: | 7451-98-1.mol |  |
| | 3',4'-DIHYDROXYPROPIOPHENONE Chemical Properties |
| Melting point | 145-146°C | | Boiling point | 375.1±27.0 °C(Predicted) | | density | 1.237±0.06 g/cm3(Predicted) | | pka | 8.75±0.31(Predicted) | | CAS DataBase Reference | 7451-98-1(CAS DataBase Reference) |
| Provider | Language |
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ALFA
| English |
| | 3',4'-DIHYDROXYPROPIOPHENONE Usage And Synthesis |
| Uses | It is an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff. | | Preparation | Obtained by Fries rearrangement of pyrocatechol dipropio-nate with aluminium chloride in chlorobenzene at 80° for 2 h (84%) or in nitrobenzene at 100° for 15 min;
Obtained by Fries rearrangement of pyrocatechol dipropionate with aluminium chloride in the presence of pyrocatechol, in nitrobenzene at 80° for 1 h (37%) or in nitromethane at r.t. for 72 h (76%)
Also obtained by Fries rearrangement of o-methoxyphenyl propionate (1 mol) by aluminium chloride (2 mol) without solvent at 140° for 2 h (51–55%) or in nitrobenzene at 80° for 30–60 min. A demethylation occurs during the reaction.
Also obtained by acylation of pyrocatechol with propionic acid
in the presence of boron trifluoride, at 150° for 2 h in a sealed tube ? (36%)
in the presence of polyphosphoric acid for 15 min in a boiling water bath ? (12%)
Preparation by demethylation of 4-hydroxy-3-methoxypropiophenone with refluxing pyridinium chloride for 10 min (80%)
Also obtained when propiovanillone was heated with an alkali sulfide under conditions used in the kraft cooking process. |
| | 3',4'-DIHYDROXYPROPIOPHENONE Preparation Products And Raw materials |
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