2-AMINO-5-FLUOROACETOPHENONE manufacturers
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| 2-AMINO-5-FLUOROACETOPHENONE Basic information | Uses |
Product Name: | 2-AMINO-5-FLUOROACETOPHENONE | Synonyms: | 1-(2-Amino-5-fluorophenyl);2-AMINO-5-FLUOROACETOPHENONE;Ethanone, 1-(2-amino-5-fluorophenyl)-;1-(2-amino-5-fluorophenyl)ethan-1-one;1-(2-AMino-5-fluorophenyl)ethanone;5-Fluoro-2-Amino-Acetophenone | CAS: | 2343-25-1 | MF: | C8H8FNO | MW: | 153.15 | EINECS: | | Product Categories: | | Mol File: | 2343-25-1.mol | |
| 2-AMINO-5-FLUOROACETOPHENONE Chemical Properties |
Melting point | 64-65 °C | Boiling point | 264.2±20.0 °C(Predicted) | density | 1.201±0.06 g/cm3(Predicted) | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | pka | 2.37±0.10(Predicted) |
| 2-AMINO-5-FLUOROACETOPHENONE Usage And Synthesis |
Uses | 1-(2-Amino-5-fluorophenyl)ethanone is a useful research chemical. | Uses | 2-Amino-5-fluoroacetophenone can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes. | Synthesis | 600 g of 2-ethynyl-4-fluoroaniline and 4 L of water were added to the reaction flask, and then 476 g of hydrochloric acid (concentration: 35%) was added, and thereaction was carried out at 50 ??C for 36 hours.After the reaction, the temperature is lowered to 20-25 ??C, the reaction solution is adjusted to pH 8-9 with 50% sodium hydroxide solution, thetemperature is controlled to not exceed 30 ??C during pH adjustment, and the filter cake is washed with 1 L of water and decompressed at 50 ??C. After drying for 12 h, 622 g of pale yellow solid was obtained, yield91.4%.HPLC purity was 99.2%. |
| 2-AMINO-5-FLUOROACETOPHENONE Preparation Products And Raw materials |
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